(±)-α-Methyl-(4-carboxyphenyl)glycine (±)-α-甲基-(4-羧基苯基)甘氨酸

CAS 146669-29-6 MFCD00210205

化学结构图

146669-29-6
SMILES: CC(N)(C1C=CC(=CC=1)C(O)=O)C(O)=O

化学属性

Mol. FormulaC10H11NO4
Mol. Weight209.20

别名和识别编码

Chemical Name(RS)-MCPG
Synonym (±)-MCPG
MDL NumberMFCD00210205
PubChem Substance ID24278286
CAS Number146669-29-6
Chemical Name Translation(±)-α-甲基-(4-羧基苯基)甘氨酸
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分类

  • {SNA} Bioactive Small Molecule Alphabetical Index, Excitatory Amino Acids, Excitatory Amino Acids - Metabotropic Antagonists, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, M, Membrane Protein Biology Tools, Metabotropic Antagonists, Neuroscience, Neurotransmission, Neurotransmitters, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 蛋白质及衍生物
  • Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Excitatory Amino Acids, Excitatory Amino Acids - Metabotropic Antagonists, GPCR Modulators, GPC

相关文献及参考

  • [2]. Fiona Yeuk-Lun Choi, et al. The effects of (RS)-MCPG on amphetamine-induced sensitization in neonatal rats.
  • Huber, K.M., et al., Effects of the metabotropic glutamate receptor antagonist MCPG on phosphoinositide turnover and synaptic plasticity in visual cortex. J. Neurosci. 18 , 1-9, (1998) 摘要
  • Rao, A.M., et al., Neuroprotection by group I metabotropic glutamate receptor antagonists in forebrain ischemia of gerbil. Neurosci. Lett. 293 , 1-4, (2000) 摘要
  • Schoepp, D.D., et al., LY354740 is a potent and highly selective group II metabotropic glutamate receptor agonist in cells expressing human glutamate receptors. Neuropharmacology 36 , 1-11, (1997) 摘要
  • Thomas, L.S., et al., Metabotropic glutamate autoreceptors of the mGlu(5) subtype positively modulate neuronal glutamate release in the rat forebrain in vitro . Neuropharmacology 39 , 1554-1566, (2000) 摘要
  • [1]. Yang B et al. Regulation of GABA Equilibrium Potential by mGluRs in Rat

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

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