Gamma-Schisandrin 五味子乙素
CAS 61281-37-6 MFCD00210555
化学结构图
SMILES: CC1CC2C=C3OCOC3=C(OC)C=2C2C(OC)=C(OC)C(=CC=2CC1C)OC
化学属性
| Mol. Formula | C23H28O6 |
|---|---|
| Mol. Weight | 400.51 |
别名和识别编码
| Chemical Name | Gamma-Schisandrin |
|---|---|
| Synonym | |
| Wiswesser Line Notation | T D5 B686 EO GO FH&&T&J CO1 L1 M1 QO1 RO1 SO1 |
| CAS Number | 61281-37-6 |
| Chemical Name Translation | 五味子乙素 |
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相关文献及参考
- [2]. Lam PY, et al. Schisandrin B as a hormetic agent for preventing age-related neurodegenerative diseases. Oxid Med Cell Longev. 2012;2012:250825.
- [3]. Zeng KW, et al. Schisandrin B exerts anti-neuroinflammatory activity by inhibiting the Toll-like receptor 4-dependent MyD88/IKK/NF-κB signaling pathway in lipopolysaccharide-induced microglia. Eur J Pharmacol. 2012 Oct 5;692(1-3):29-37.
- [4]. Liu Z, et al. Schisandrin B attenuates cancer invasion and metastasis via inhibiting epithelial-mesenchymal transition. PLoS One. 2012;7(7):e40480.
- [5]. Zhu S, et al. Protective effect of schisandrin B against cyclosporine A-induced nephrotoxicity in vitro and in vivo. Am J Chin Med. 2012;40(3):551-66.
- [1]. Checker R, et al. Schisandrin B exhibits
- [1]. Checker R, et al. Schisandrin B exhibits anti-inflammatory activity through modulation of the redox-sensitive transcription factors Nrf2 and NF-κB. Free Radic Biol Med. 2012 Oct 1;53(7):1421-30.
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 2 gm/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex)
REFERENCE :
CMJODS Chinese Medical Journal (Beijing, English Edition). (China
International Book Trading Corp., POB 2820, Beijing, Peop. Rep. China) V.1-
1975- Adopted vol. no. 92 in 1979. Volume(issue)/page/year: 93,41,1980 GHS Symbol
