MAGNESIUM PEMOLINE
CAS 18968-99-5 MFCD00221706
化学结构图
SMILES: NC1=NC(=O)C(O1)C1C=CC=CC=1.O[Mg]O
化学属性
| Mol. Formula | C9H10MgN2O4 |
|---|---|
| Mol. Weight | 234.52 |
别名和识别编码
| Chemical Name | Pemoline magnesium |
|---|---|
| Wiswesser Line Notation | T5OYMV EHJ BUM ER &-MG- |
| Synonym | 4(5H)-Oxazolidinone, 2-imino-5-phenyl-, mixt. with magnesium hydroxide (2-Imino-5-phenyl-4-oxazolidinonato(2-))diaquomagnesium 2-Imino-5-phenyl-4-oxazolidinone magnesium chelate Bis(aquo)-N,N'-(2-imino-5-phenyl-4-oxazolidinone)magnesium (II) Pemolin and magnesium hydroxide Pemoline magnesium chelate Cylert 4-Oxazolidinone, 2-imino-5-phenyl-, mixt. with magnesium hydroxide Magnesium pemoline Tamilan Abbott 30400 |
| CAS Number | 18968-99-5 |
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安全信息
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - child DOSE/DURATION : 149 mg/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) Gastrointestinal - nausea or vomiting REFERENCE : CPEDAM Clinical Pediatrics (Philadelphia). (Lippincott/Harper, Journal Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740) V.1- 1962- Volume(issue)/page/year: 18,761,1979
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 487 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - other changes REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 181,441,1969
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 500 mg/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) Behavioral - irritability Lungs, Thorax, or Respiration - other changes REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 181,441,1969
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 485 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD
