ST638
CAS 107761-24-0 MFCD00236446
化学结构图
SMILES: CCOC1C=C(/C=C(/C#N)\C(N)=O)C=C(CSC2C=CC=CC=2)C=1O
化学属性
| Mol. Formula | C19H18N2O3S |
|---|---|
| Mol. Weight | 354.42 |
| Melting Point | 134-135.5 °C |
别名和识别编码
| Chemical Name | ST638 |
|---|---|
| Synonym | α-Cyano-(3-ethoxy-4-hydroxy-5-phenylthiomethyl)cinnamide 2-Cyano-3-(3-ethoxy-4-hydroxy-5-((phenylthio)methyl)phenyl)-2-propenamide ST 638 ST638 alpha-Cyano-3-ethoxy-4-hydroxy-5-(phenylthiomethyl)cinnamide α-Cyano-(3-ethoxy-4-hydroxy-5-phenylthiomethyl)cinnamide |
| MDL Number | MFCD00236446 |
| CAS Number | 107761-24-0 |
| Beilstein Registry Number | 5634581 |
| PubChem Substance ID | 329824465 |
| Chemical Name Translation |
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分类
- {SNA} Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, Receptor Tyrosine Kinase Biology, Receptor Tyrosine Kinase Inhibitors, Vascular Endothelial Growth Factor Receptor (VEGFR)
- {SNA} Bioactive Small Molecule Alphabetical Index, Kinase/Phosphatase Biology, Receptor Tyrosine Kinase Biology, Receptor Tyrosine Kinase Inhibitors, S, Vascular Endothelial Growth Factor Receptor (VEGFR), 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology, Receptor Tyrosine Kinase Biology, Receptor Tyrosine Kinase Inhibitors, Vascular Endothelial Growth Factor Receptor (VEGFR)
相关文献及参考
- Watanabe, T., et al. , Inhibitors for protein-tyrosine kinases, ST638 and genistein: induce differentiation of mouse erythroleukemia cells in a synergistic manner. Exp. Cell Res. 183 , 335-342 , (1989)
安全信息
GHS Symbol
- H302 Harmful if swallowed 吞食有害
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #93-00938
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #93-00938
