(R)-2,3-Dihydroxypropyl 4-methylbenzenesulfonate (R)-对甲苯磺酸-1-甘油酯

CAS 41274-09-3 MFCD00270084

化学结构图

41274-09-3
SMILES: CC1=CC=C(C=C1)S(=O)(=O)OC[C@H](O)CO

化学属性

Mol. FormulaC10H14O5S
Mol. Weight246.28

别名和识别编码

Chemical Name(R)-2,3-Dihydroxypropyl 4-methylbenzenesulfonate
CAS Number41274-09-3
Synonym (R)-1-Tosyloxyglycerol (R)-2,3-二羟基丙基对甲苯磺酸酯 (R)-3-甲苯磺酰氧基-1,2-丙二醇 sn-甘油基 1-(对甲苯磺酸酯) (R)-3-(Tosyloxy)-1,2-propanediol (R)-对甲苯磺酸-1-甘油酯 (R)-1,2,3-Propanetriol 4-methylbenzenesulfonate (R)-3-(p-Toluenesulfonyloxy)-1,2-propanediol
MDL NumberMFCD00270084
Chemical Name Translation(R)-对甲苯磺酸-1-甘油酯
PubChem Substance ID329799902
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分类

  • Sulfur & Selenium Compounds
  • Chiral Reagents
  • Aromatics
  • {SNA} Alcohols, Asymmetric Synthesis, Chemical Synthesis, Chiral Building Blocks, Organic Building Blocks

产品应用

  • A chiral synthon for general asymmetric synthesis. An intermediate for the synthesis of chiral aryloxypropanolamines, which make up the majority of known potent beta-adrenergic blockers.

相关文献及参考

  • Fuji, M., et al.: Chem. Pharm. Bull., 40, 2353 (1992),
  • Meerpoel, L., et al.: J. Med. Chem., 48, 2184 (2005),

安全信息

GHS Symbol
WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
Hazard Codes Xi
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类


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