N-(3-Chloro-4-(4-Chlorophenoxy)Phenyl)-2-Hydroxy-3,5-DIIodobenzamide 3-氯-4-(对氯苯氧基)-3,5-二碘水杨酰苯胺
CAS 22662-39-1 MFCD00682899
化学结构图
SMILES: OC1C(=CC(I)=CC=1I)C(=O)NC1=CC(Cl)=C(C=C1)OC1C=CC(Cl)=CC=1
化学属性
| Mol. Formula | C19H11Cl2I2NO3 |
|---|---|
| Mol. Weight | 626 |
| Melting Point | 173.0 to 177.0 deg-C |
别名和识别编码
| Chemical Name | N-(3-Chloro-4-(4-Chlorophenoxy)Phenyl)-2-Hydroxy-3,5-DIIodobenzamide |
|---|---|
| CAS Number | 22662-39-1 |
| Synonym | Bovanide 3'-Chloro-4'-(p-chlorophenoxy)-3,5-diiodosalicylanilide Flukanide 雷复尼特 Benzamide, N-(3-chloro-4-(4-chlorophenoxy)phenyl)-2-hydroxy-3,5-diiodo- Rafoxanide ######## MK-990 Duofas Ranide 3'-Chloro-4'-(4-chlorophenoxy)-3,5-diiodosalicylanilide |
| MDL Number | MFCD00682899 |
| PubChem Substance ID | 172089089 |
| EC Number | 245-148-9 |
| Chemical Name Translation | 3-氯-4-(对氯苯氧基)-3,5-二碘水杨酰苯胺 |
| Wiswesser Line Notation | QR BI DI FVMR CG DOR DG |
| Beilstein Registry Number | 2228187 |
| Reaxys-RN | 2228187 |
| Merck Number | 8097 |
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分类
- Amines
- Aromatics
- Pharmaceuticals
- Intermediates & Fine Chemicals
- {SA} Alphabetic, Analytical Standards, Analytical/Chromatography, Chromatography, Environmental Standards, Insecticides, Others, Pesticides, Pesticides & Metabolites, R
- {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Chromatography, Environmental Standards, Insecticides, Others, Pesticides & Metabolites, Pesticides Standards, R
产品应用
- Rafoxanide is a thyroid hormone receptor.
相关文献及参考
- Bernal, J., et al.: Vitam. Horm., 71, 95 (2005),
- Fujimoto, N., et al.: J. Endocrinol., 181, 77 (2005),
- Hamers, T., et al.: Toxicol. Sci., 92, 157 (2006),
安全信息
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Mammal - cattle
DOSE/DURATION : 80 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
REMVAY Revue d'Elevage et de Medicine Veterinaire des Pays Tropicaux.
(Editions Vigot, 23 rue de l'Ecole-de-Medecine, F-75006 Paris, France) V.1-
1947- Volume(issue)/page/year: 29,31,1976