CA-074 (S)-1-((2S,3S)-3-甲基-2-((2S,3S)-3-(丙基氨基甲酰基)环氧乙烷-2-甲酰胺基)戊酰基)吡咯烷-2-羧酸
CAS 134448-10-5 MFCD00797531
化学结构图
SMILES: C[C@@H](CC)[C@H](NC(=O)[C@H]1O[C@@H]1C(=O)NCCC)C(=O)N1CCC[C@H]1C(O)=O
化学属性
| Mol. Formula | C18H29N3O6 |
|---|---|
| Mol. Weight | 383.44 |
别名和识别编码
| Chemical Name | CA-074 |
|---|---|
| Synonym | (L-3-trans-(Propylcarbamyl)oxirane-2-carbonyl)-L-isoleucyl-L-proline |
| MDL Number | MFCD00797531 |
| PubChem Substance ID | 24892580 |
| CAS Number | 134448-10-5 |
| Chemical Name Translation | (S)-1-((2S,3S)-3-甲基-2-((2S,3S)-3-(丙基氨基甲酰基)环氧乙烷-2-甲酰胺基)戊酰基)吡咯烷-2-羧酸 |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- A to C, Apoptosis and Cell Cycle, Application Index, Bioactive Small Molecules, Biochemicals and Reagents, C-CH, Cathepsin B, Cathepsin/Granzyme Inhibitors & Substrates, Cathepsins and Granzymes, Cell Biology, Cell Signaling Enzymes, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Inhibitors, Lysosomal Proteases, Peptides and Proteins, Peptides for Cell Biology, Protease Inhibitor Specificity Index, Protease Inhibitors, Proteasome, Calpain and Lysosomal Proteases
- {SNA} A to C, Apoptosis and Cell Cycle, Applic
相关文献及参考
- [2]. Montaser M, et al. CA-074, but not its methyl ester CA-074Me, is a selective inhibitor of cathepsin B within living cells. Biol Chem. 2002 Jul-Aug;383(7-8):1305-8.
- [3]. Yamashima T, et al. Inhibition of ischaemic hippocampal neuronal death in primates with cathepsin B inhibitor CA-074: a novel strategy for neuroprotection based on 'calpain-cathepsin hypothesis'. Eur J Neurosci. 1998 May;10(5):1723-33.
- Murata, M., et al., Novel epoxysuccinyl peptides. Selective inhibitors of cathepsin B, in vitro. FEBS Lett. 280 , 307, (1991) 摘要
- [1]. Towatari T, et al. Novel epoxysuccinyl peptides. A selective inhibitor of cathepsin B, in vivo. FEBS Lett. 1991 Mar 25;280(2):311-5.
- [1]. Towatari T, et al. Novel epoxysuccinyl peptides. A selective inhibitor of cathepsin B, in vivo. FEBS Lett. 1991 Mar 25;280(2):311-5.
- [2]. Montaser M, et al. CA-074, but not its methyl ester CA-074Me, is a selective inhibitor of cathepsin B within living cells. Biol
