Mizolastine 咪唑斯汀
CAS 108612-45-9 MFCD00864625
化学结构图
SMILES: CN(C1CCN(CC1)C1=NC2C=CC=CC=2N1CC1C=CC(F)=CC=1)C1NC(=O)C=CN=1
化学属性
| Mol. Formula | C24H25FN6O |
|---|---|
| Mol. Weight | 432.49 |
别名和识别编码
| Chemical Name | Mizolastine |
|---|---|
| CAS Number | 108612-45-9 |
| Synonym | 2-[[1-[1-[(4-Fluorophenyl)methyl]-1H-benzimidazol-2-yl]-4-piperidinyl]methylamino]- 4(1H)-pyrimidinone MKC 431 Mistamine Mizollen SL 850324 Zolistan |
| Chemical Name Translation | 咪唑斯汀 |
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信息真实价格透明
资金保障
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分类
- Aromatics
- Heterocycles
- Inhibitors
- Pharmaceuticals
- Intermediates & Fine Chemicals,
产品应用
- A highly selective histamine H1-receptor antagonist (with no anticholinergic, antiadrenergic, or antiserotonin activity) for use in the treatment of allergic disorders, especially rhinitis and urticar
相关文献及参考
- Simons, F.E.R.: Clin. Alp. Allergy, 29, 3 (1999); Brostoff, J. et al.: Allergy, 51, 251 (1996); Gensthaler, B.M.: Pharm. Zeit., 143, 228 (1998);
- [1]. Prakash A, et al. Mizolastine: a review of its use in allergic rhinitis and chronic idiopathic urticaria. BioDrugs. 1998 Jul;10(1):41-63.
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - species unspecified DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4820710
GHS Symbol
