Cinalukast
CAS 128312-51-6 MFCD00864778
化学结构图
SMILES: CCC(CC(=O)NC1C=C(/C=C/C2=NC(=CS2)C2CCC2)C=CC=1)(CC)C(O)=O
化学属性
| Mol. Formula | C23H28N2O3S |
|---|---|
| Mol. Weight | 412.55 |
别名和识别编码
| Chemical Name | Cinalukast |
|---|---|
| CAS Number | 128312-51-6 |
| Synonym | (E)-4-[[3-(2-(4-Cyclobutyl-2-thiazolyl)ethenyl)phenyl]amino]-2,2-diethyl-4-oxobutanoic acid Ro 24-5913 4-[[3-[(1E)-2-(4-Cyclobutyl-2-thiazolyl)ethenyl]phenyl]amino]-2,2-diethyl-4-oxo-Butanoic Acid Ro 24-5913 |
| MDL Number | MFCD00864778 |
| PubChem Substance ID | 24724447 |
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分类
- {SNA} Approved Therapeutics/Drug Candidates, Arachidonic Acid Cascade, Bioactive Small Molecule Alphabetical Index, CI-CZ, Diversification Ready Pharma-Developed Compounds, Leukotrienes, Lipids in Cell Signaling, Roche, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- {SNA} Approved Therapeutics/Drug Candidates, Arachidonic Acid Cascade, Bioactive Small Molecules, CI-CY, Cell Biology, Cell Signaling and Neuroscience, Leukotrienes, Lipids in Cell Signaling, Roche
- Approved Therapeutics/Drug Candidates, Arachidonic Acid Cascade, Bioactive Small Molecules, CI-CY, Cell Biology,
产品应用
- A novel leukotriene D4 antagonist.
相关文献及参考
- O'Donnell, M., et al.: J. Pharmacol. Exp. Ther., 259, 751 (1991),
- Jones, T., et al.: J. Physiol. Pharmacol., 73, 191 (1995),
- Kawano, T., et al.: J. Allergy Clin. Immunol., 112, 369 (2003),
- Maehr, H. and Yang, R., A convergent synthesis of Ro24-5913, a novel leukotriene D 4 antagonist. Tetrahedron Lett. 37 , 5445-5448, (1996)
