2,1,3-Benzothiadiazole,5-chloro-4-(2-imidazolin-2-ylamino)-
CAS 51322-75-9 MFCD00865192
化学结构图
SMILES: ClC1C=CC2=NSN=C2C=1NC1NCCN=1
化学属性
| Mol. Formula | C9H8ClN5S |
|---|---|
| Mol. Weight | 253.73 |
别名和识别编码
| Chemical Name | 2,1,3-Benzothiadiazole,5-chloro-4-(2-imidazolin-2-ylamino)- |
|---|---|
| Wiswesser Line Notation | T56 BNSNJ FM- BT5M CN BUTJ& GG |
| Synonym | 2,1,3-Benzothiadiazole-4-amine, |
| Beilstein Registry Number | 0618691 |
| CAS Number | 51322-75-9 |
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相关文献及参考
- [1]. Kamen L, et al. A practical overview of tizanidine use for spasticity secondary to multiple sclerosis, stroke, and spinal cord injury. Curr Med Res Opin. 2008 Feb;24(2):425-39.
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 235 mg/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) Behavioral - ataxia Skin and Appendages - hair REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 30,793,1980
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 600 mg/kg TOXIC EFFECTS : Behavioral - altered sleep time (including change in righting reflex) Behavioral - ataxia Skin and Appendages - hair REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 30,793,1980
