Irsogladine 伊索拉定
CAS 57381-26-7 MFCD00866871
化学结构图
SMILES: NC1=NC(=NC(N)=N1)C1C=C(Cl)C=CC=1Cl
化学属性
| Mol. Formula | C9H7Cl2N5 |
|---|---|
| Mol. Weight | 256.11 |
别名和识别编码
| Chemical Name | Irsogladine |
|---|---|
| Synonym | 2,4-Diamino-6-(2,5-dichlorophenyl)-1,3,5-triazine 6-(2,5-Dichlorophenyl)-1,3,5-triazine-2,4-diamine |
| CAS Number | 57381-26-7 |
| Chemical Name Translation | 伊索拉定 |
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相关文献及参考
- [2]. Kawasaki, Y., et al., Irsogladine malate up-regulates gap junctional intercellular communication between pancreatic cancer cells via PKA pathway. Pancreas, 2002. 25(4): p. 373-7.
- [3]. Kyoi, T., et al., Phosphodiesterase inhibition by a gastroprotective agent irsogladine: preferential blockade of cAMP hydrolysis. Life Sci, 2004. 75(15): p. 1833-42.
- [1]. Ren, C.J., et al., Irsogladine maleate inhibits angiogenesis in wild-type and plasminogen activator-deficient mice. J Surg Res, 1998. 77(2): p. 126-31.
- [1]. Ren, C.J., et al., Irsogladine maleate inhibits angiogenesis in wild-type and plasminogen activator-deficient mice. J Surg Res, 1998. 77(2): p. 126-31.
- [2]. Kawasaki, Y., et al., Irsogladine malate up-regulates gap junctional intercellular communication between pancreatic cancer cells via PKA pathway. Pancreas, 2002. 25(4): p. 373-7.
- [3]. Kyoi, T., et al., Phosphodiesterase inhibition by a gastroprotective agent irsogladine: pre
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1740 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4657907
