2-(2,3-Dichloro-4-(Thiophene-2-Carbonyl)Phenoxy)Acetic Acid 2-(2,3-二氯-4-(噻吩-2-羰基)苯氧基)乙酸
CAS 40180-04-9 MFCD00867339
化学结构图
SMILES: OC(=O)COC1C=CC(=C(Cl)C=1Cl)C(=O)C1=CC=CS1
化学属性
| Mol. Formula | C13H8Cl2O4S |
|---|---|
| Mol. Weight | 331 |
别名和识别编码
| Chemical Name | 2-(2,3-Dichloro-4-(Thiophene-2-Carbonyl)Phenoxy)Acetic Acid |
|---|---|
| CAS Number | 40180-04-9 |
| Synonym | ######## (2,3-Dichloro-4-(2-thenoyl)phenoxy)acetic acid (2,3-Dichloro-4-(2-thienylcarbonyl)phenoxy)acetic acid (2,3-Dichloro-4-(2-thiophenecarbonyl)phenoxy)acetic acid 4-(2-Theonyl)-2,3-dichlorphenoxyessigsaeure 4-(2-Thienylketo)-2,3-dichlorophenoxyacetic acid ANP 3624 CE 3624 Diflurex FR 3068 SKF 62698 Selacryn Thienylic acid Ticrex Ticrynafen Ticrynafen Tienylic acid [2,3-Dichloro-4-(2-thienylcarbonyl)phenoxy]-acetic acid Tienilic Acid Tienilic acid Tienilico acido |
| MDL Number | MFCD00867339 |
| Chemical Name Translation | 2-(2,3-二氯-4-(噻吩-2-羰基)苯氧基)乙酸 |
| Wiswesser Line Notation | T5SJ BVR BG CG DO1VQ |
| Beilstein Registry Number | 1260086 |
| EC Number | 254-826-3 |
| PubChem Substance ID | 329825452 |
信息真实价格透明
资金保障
专业采购外包团队在线服务
信息真实价格透明
资金保障
专业采购外包团队在线服务
品牌质保精细包装
现货库存
一流品牌服务
分类
- {SNA} Cell Biology, Cell Signaling and Neuroscience, Drug and Xenobiotic Metabolism, Multi-Drug Resistance and Drug Metabolism, New Products, Substrates, Inducers, Inhibitors
- Sulfur & Selenium Compounds
- Heterocycles
- Pharmaceuticals
- {SNA} Bioactive Small Molecule Alphabetical Index, Drug and Xenobiotic Metabolism, Multi-Drug Resistance and Drug Metabolism, Substrates, Inducers, Inhibitors, T, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
- Intermediates & Fine Chemicals
- Aromatics
产品应用
- Tienilic Acid is a heterocyclic derivative of phenoxyacetic acid. Tienilic acid is used as diuretic, uricosuric, antihypertensive.
相关文献及参考
- Kerremans, A.L., et al.: Eur. J. Clin. Pharmacol., 22, 515 (1982),
安全信息
TYPE OF TEST : LD50 - Lethal
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - man DOSE/DURATION : 3571 ug/kg TOXIC EFFECTS : Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Kidney, Ureter, Bladder - urine volume decreased REFERENCE : CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher information, see JTCTDW. Volume(issue)/page/year: 18,425,1981
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 225 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3758506
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 318 mg/kg TOXIC EFFECTS : Kidney, Ureter, Bladder - urine volume increased REFERENCE : DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 13,257,1988
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Human - woman DOSE/DURATION : 5 mg/kg TOXIC EFFECTS : Gastrointestinal - nausea or vomiting Kidney, Ureter, Bladder - urine volume decreased REFERENCE : NEJMAG New England Journal of Medicine. (Massachusetts Medical Soc., 10 Shattuck St., Boston, MA 02115) V.198- 1928- Volume(issue)/page/year: 301,1179,1979
TYPE OF TEST : TDLo - Lowest published toxic
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Rodent - hamster Lung DOSE/DURATION : 10 umol/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 157,1,1985
TYPE OF TEST : Mutation in mammalian somatic cells TEST SYSTEM : Rodent - hamster Lung DOSE/DURATION : 100 umol/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 157,1,1985
- R22 Harmful if swallowed 吞咽有害
