Cabergoline 卡麦角林

CAS 81409-90-7 MFCD00867887

化学结构图

81409-90-7
SMILES: CN(C)CCCN(C(=O)[C@@H]1CN(CC=C)[C@H]2CC3=CNC4C=CC=C([C@@H]2C1)C3=4)C(=O)NCC |&1:9,15,25|

化学属性

Mol. FormulaC26H37N5O2
Mol. Weight452

别名和识别编码

Chemical NameCabergoline
Synonym Cabergoline 1-[(6-Allylergoline-8β-yl)carbonyl]-1-[3-(dimethylamino)-propyl]-3-ethylurea 1-Ethyl-3-(3'-dimethylaminopropyl)-3-(6'-allylergoline-8'β-carbonyl)urea Cabaser Dostinex FCE-21336
MDL NumberMFCD00867887
Chemical Name Translation卡麦角林
CAS Number81409-90-7
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分类

  • {SNA} Agonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, C-CH, Cell Biology, Cell Signaling and Neuroscience, Dopaminergics, Johnson & Johnson, Neuroscience, Neurotransmission, Neurotransmitters, Pfizer Compounds
  • {SNA} Agonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, C-CH, Dopaminergics, Johnson & Johnson, Neuroscience, Neurotransmission, Neurotransmitters, Pfizer Compounds, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学

相关文献及参考

  • [2]. Jefferson F, et al. A dopamine receptor d2-type agonist attenuates the ability of stress to alter sleep in mice. Endocrinology. 2014 Nov;155(11):4411-21.
  • [1]. Odaka H, et al. Cabergoline, dopamine D2 receptor agonist, prevents neuronal cell death under oxidative stress via reducing excitotoxicity. PLoS One. 2014 Jun 10;9(6):e99271.
  • [1]. Odaka H, et al. Cabergoline, dopamine D2 receptor agonist, prevents neuronal cell death under oxidative stress via reducing excitotoxicity. PLoS One. 2014 Jun 10;9(6):e99271.
  • [2]. Jefferson F, et al. A dopamine receptor d2-type agonist attenuates the ability of stress to alter sleep in mice. Endocrinology. 2014 Nov;155(11):4411-21.

安全信息

Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
GHS Symbol
WGK Germany3
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H302 Harmful if swallowed 吞食有害
  • H319 Causes serious eye irritation 严重刺激眼睛
RTECSKE6167600
Signal word Warning
Hazard Codes Xi
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类


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