(Ethoxycarbonyl)(3-Morpholino-1,2,3-Oxadiazol-3-Ium-5-Yl)Amide (乙氧基羰基)(3-吗啉-1,2,3-恶二唑-3-鎓-5-基)胺

CAS 25717-80-0 MFCD00869301

化学结构图

25717-80-0
SMILES: CCOC(=O)/N=C1/C=[N+]([N-]O/1)N1CCOCC1

化学属性

Mol. FormulaC9H14N4O4
Mol. Weight242
Melting Point139.0 to 143.0 deg-C

别名和识别编码

Chemical Name(Ethoxycarbonyl)(3-Morpholino-1,2,3-Oxadiazol-3-Ium-5-Yl)Amide
CAS Number25717-80-0
Synonym Sydnone imine, N-(ethoxycarbonyl)-3-(4-morpholinyl)- Corvaton ######## Morial N-(Ethoxycarbonyl)-3-(4-morpholino)sydnone imine SIN-10 Morsydomine N-​(Ethoxycarbonyl)​-​3-​(4-​morpholino)​sydnone imine SIN-10 Molsidomine SIN-10 N-(Ethoxycarbonyl)-3-(4-morpholinyl)sydnone imine Molsidolat Motazomin N-(Ethoxycarbonyl)-3-(4-morpholino)sydnone imine SIN-10
MDL NumberMFCD00869301
PubChem Substance ID253661632
EC Number247-207-4
Wiswesser Line NotationT5NNOYJ A- AT6N DOTJ& DUNVO2 &GH
Beilstein Registry Number3996945
Chemical Name Translation(乙氧基羰基)(3-吗啉-1,2,3-恶二唑-3-鎓-5-基)胺
Reaxys-RN3996945
Merck Number6234
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • Nitric Oxide Reagents
  • {SNA} Application Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling Enzymes, Cell Signaling and Neuroscience, Enzyme Substrates, Enzymes, Inhibitors, and Substrates, M, NO Donors, Nitric Oxide Donors, Nitric Oxide Metabolism, Nitric Oxide Synthase/NO Donor, Nitric Oxide and Cell Stress, Substrates by Enzyme
  • Heterocycles
  • {SNA} Application Index,
  • Pharmaceuticals
  • {SNA} Application Index, Bioactive Small Molecule Alphabetical Index, Cell Signaling Enzymes, Enzyme Substrates, M, NO Donors, Nitric Oxide Donors, Nitric Oxide Metabolism,
  • Intermediates & Fine Chemicals
  • {SNA} Application Index,

产品应用

  • Molsidomine is an antianginal agent. Molsidomine is an effective therapeutic agents in the treatment of angina pectoris. Molsidomine is a sydnonimine derivative that acts as a heterocyclic direct nitr

相关文献及参考

  • Tanayama, S. et al.: Xenobiotica, 4, 175 (1974); Yamada, M. et al.: Chem. Pharmac. Bull., 35, 3390 (1987); Messin, R. et al.: Adv. Ther., 23, 107 (2006);

安全信息

WGK Germany3
GHS Symbol
Hazard statements
  • H302 Harmful if swallowed 吞食有害
RTECSWU7677400
Signal word
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
Hazard Codes Xn
Risk Statements
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 910 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - cyanosis
   Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
   TOIZAG Toho Igakkai Zasshi.  Journal of Medical Society of Toho University.
   (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143,
   Japan)  V.1-    1954-  Volume(issue)/page/year: 17,26,1

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 750 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - cyanosis
   Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
   TOIZAG Toho Igakkai Zasshi.  Journal of Medical Society of Toho University.
   (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143,
   Japan)  V.1-    1954-  Volume(issue)/page/year: 17,26,1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        :

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - cyanosis
   Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
   TOIZAG Toho Igakkai Zasshi.  Journal of Medical Society of Toho University.
   (Toho Daigaku Igakkai, 21-16, Omori-nishi, 5-chome, Ota-ku, Tokyo 143,
   Japan)  V.1-    1954-  Volume(issue)/page/year: 17,

Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P301+P312+P330
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Storage condition 0-10°C

系列性分类


相关产品推荐