(12Z,6R,7R,8E,13E,15E,17S)-17-Hydroxy-6-Isopropyl-7,15-Dimethyl-32,33-Dihydro-31H-5-Oxa-11-Aza-1(4,2)-Oxazola-3(1,5)-Pyrrolacycloicosaphane-8,13,15-Triene-2,4,10,19-Tetraone (12Z,6R,7R,8E,13E,15E,17S)-17-羟基-6-异丙基-7,15-二甲基-32,33-二氢-31H-5-氧杂-11-氮杂-1(4,2)-噁唑-3(1,5)-吡咯环二十碳烷-8,13,15-三烯-2,4,10,19-四酮

CAS 21411-53-0 MFCD00869411

化学结构图

21411-53-0
SMILES: CC1C=CCNC(=O)C=C[C@@H](C)[C@H](OC(=O)C2=CCCN2C(=O)C2=COC(CC(=O)C[C@H](O)C=1)=N2)C(C)C |c:34,t:2,8|

化学属性

Mol. FormulaC28H35N3O7
Mol. Weight526
Melting Point165 - 170

别名和识别编码

Chemical Name(12Z,6R,7R,8E,13E,15E,17S)-17-Hydroxy-6-Isopropyl-7,15-Dimethyl-32,33-Dihydro-31H-5-Oxa-11-Aza-1(4,2)-Oxazola-3(1,5)-Pyrrolacycloicosaphane-8,13,15-Triene-2,4,10,19-Tetraone
CAS Number21411-53-0
Synonym ######## Mikamycin A Staphylomycin Mikamycin A Staphylomycin Virginiamycin M1
MDL NumberMFCD00869411
PubChem Substance ID24900736
EC Number244-376-6
Chemical Name Translation(12Z,6R,7R,8E,13E,15E,17S)-17-羟基-6-异丙基-7,15-二甲基-32,33-二氢-31H-5-氧杂-11-氮杂-1(4,2)-噁唑-3(1,5)-吡咯环二十碳烷-8,13,15-三烯-2,4,10,19-四酮
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分类

  • Chiral Reagents
  • Heterocycles
  • {SNA} Antibacterial, Antibiotics A to Z, Antibiotics T-Z, Chemical Structure Class, Interferes with Protein Synthesis, L - Z, Macrolides, Mechanism of Action, Spectrum of Activity, 抗生素, 生化试剂
  • Pharmaceuticals
  • {SNA} Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics T-Z, Chemical Structure Class, Interferes with Protein Synthesis, L - Z, Macrolides, Mechanism of Action, Spectrum of Activity
  • Intermediates & Fine Chemicals

产品应用

  • Macrolactone antibiotic. Antibacterial; growth promotant.

相关文献及参考

  • Crooy, P., et al.: J. Antibiot., 25, 371 (1972),
  • Allington, D., et al.: Clin. Therap., 23, 24 (2001),
  • Eeman, M., et al.: Langmuir, 22, 11337 (2006),

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
GHS Symbol
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触;
Precautionary statements
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛,皮肤或衣服。

系列性分类


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