1'-Hydroxymidazolam α-羟基咪达唑仑溶液,100ppm,1ml/支

CAS 59468-90-5 MFCD00871458

化学结构图

59468-90-5
SMILES: OCC1=NC=C2CN=C(C3C=C(Cl)C=CC=3N12)C1=CC=CC=C1F

化学属性

Mol. FormulaC18H13ClFN3O
Mol. Weight342

别名和识别编码

Chemical Name1’-Hydroxy Midazolam
CAS Number59468-90-5
Synonym 8-Chloro-6-(2-fluorophenyl)-4H-imidazo[1,5-a][1,4]benzodiazepine-1-methanol 1'-Hydroxymidazolam
MDL NumberMFCD00871458
PubChem Substance ID24724655
Chemical Name Translationα-羟基咪达唑仑溶液,100ppm,1ml/支
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分类

  • Aromatics
  • Heterocycles
  • Metabolites & Impurities
  • Pharmaceuticals
  • Intermediates & Fine Chemicals,
  • {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Drug and Xenobiotic Metabolism, H, Multi-Drug Resistance and Drug Metabolism, Substrates, Inducers, Inhibitors

产品应用

  • A metabolite of Midazolam (M343000).

相关文献及参考

  • [2]. Balk M, et, al. Differential depression of neuronal network activity by midazolam and its main metabolite 1-hydroxymidazolam in cultured neocortical slices. Sci Rep. 2017 Jun 14; 7(1): 3503.
  • Dundee, J., et al.: Drugs, 28, 519
  • [1]. Hasegawa T, et, al. Increase in the systemic exposure of primary metabolites of Midazolam in rat arising from CYP inhibition or hepatic dysfunction. Drug Metab Pharmacokinet. 2017 Feb; 32(1): 69-76.
  • [1]. Hasegawa T, et, al. Increase in the systemic exposure of primary metabolites of Midazolam in rat arising from CYP inhibition or hepatic dysfunction. Drug Metab Pharmacokinet. 2017 Feb; 32(1): 69-76.
  • [2]. Balk M, et, al. Differential depression of neuronal network activity by midazolam and its main metabolite 1-hydroxymidazolam in cultured neocortical slices. Sci Rep. 2017 Jun 14; 7(1): 3503.

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类


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