NORVERAPAMIL
CAS 67018-85-3 MFCD00871831
化学结构图
SMILES: COC1=CC(=CC=C1OC)C(CCCNCCC1C=C(OC)C(=CC=1)OC)(C#N)C(C)C
化学属性
| Mol. Formula | C26H36N2O4 |
|---|---|
| Mol. Weight | 440.58 |
别名和识别编码
| Chemical Name | NORVERAPAMIL |
|---|
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资金保障
专业采购外包团队在线服务
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相关文献及参考
- [2]. Pauli-Magnus C, et al. Characterization of the major metabolites of verapamil as substrates and inhibitors of P-glycoprotein. J Pharmacol Exp Ther. 2000 May;293(2):376-82.
- [3]. Wang J et al. A semi-physiologically-based pharmacokinetic model characterizing mechanism-based auto-inhibition to predict stereoselective pharmacokinetics of verapamil and its metabolite norverapamil in human. Eur J Pharm Sci. 2013 Nov 20;50(3-4):290-302.
- [4]. Choi DH, et al. Effects of simvastatin on the pharmacokinetics of verapamil and its main metabolite, norverapamil, in rats. Eur J Drug Metab Pharmacokinet. 2009 Jul-Sep;34(3-4):163-8.
- [1]. Adams KN, et al. Verapamil, and its metabolite norverapamil, inhibit macrophage-induced, bacterial efflux pump-me
- [1]. Adams KN, et al. Verapamil, and its metabolite norverapamil, inhibit macrophage-induced, bacterial efflux pump-mediated tolerance to multiple anti-tubercular drugs. J Infect Dis. 2014 Aug 1;210(3):456-66.
