Trovafloxacin mesylate
CAS 147059-75-4 MFCD00913361
化学结构图
SMILES: CS(O)(=O)=O.N[C@@H]1[C@H]2CN(C[C@H]21)C1=NC2=C(C=C1F)C(=O)C(=CN2C1=CC=C(F)C=C1F)C(O)=O |&1:6,7,11|
化学属性
| Mol. Formula | C20H15F3N4O3· CH3SO3H |
|---|---|
| Mol. Weight | 512.46 |
别名和识别编码
| Chemical Name | Trovafloxacin mesylate |
|---|---|
| CAS Number | 147059-75-4 |
| Synonym | (1α,5α,6α)-7-(6-Amino-3-azabicyclo[3.1.0]hex-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid methanesulfonate CP-99219-27 Trovafloxacin methanesulfonate CP 99219-27 7-[(1?,5?,6?)-6-Amino-3-azabicyclo[3.1.0]hex-3-yl]-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid Methanesulfonate CP 99219 Trovafloxacin mesylate Trovafloxacin Methanes |
| MDL Number | MFCD00913361 |
| Chemical Name Translation |
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分类
- Chiral Reagents
- Heterocycles
- Pharmaceuticals
- Pfizer compounds
- Intermediates & Fine Chemicals
- Amines
- {SNA} Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Immune Cell Signaling and Blood, Immune System Regulation, Immunomodulators and Antibiotics, Pfizer Compounds, T
- {SNA} Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Immune Cell Signaling and Blood, Immune System Regulation, Immunomodulators and Antibiotics, Pfizer Compounds, T, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
产品应用
- Fluorinated quinolone antibacterial. Trovafloxacin mesylate blocks the activity of DNA gyrase and topoisomerase IV, enzymes essential in the repliction, transcription, and repair of bacterial DNA.
相关文献及参考
- Neu, H.C., et al.: Clin. Antimicrob. Agents Chemother., 38, 2615 (1994),
- Liguori, M.J., et al.: Hepatology, 41, 177 (2005),
安全信息
GHS Symbol
- P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
- H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R63 Possible risk of harm to the unborn child 可能危害未出生婴儿
- R34 Causes burns 会导致灼伤
