Sb-203580 4-(4-(4-氟苯基)-2-(4-(甲基亚磺酰)苯基)-1H-咪唑-5-基)吡啶
CAS 152121-47-6 MFCD00922198
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信息真实价格透明
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分类
- Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Kinase/Phosphatase Biology, L to O, MAP Kinase, MAPK-Activated Protein Kinase (MAPKAP Kinase), Phosphorylation Analysis, Post-Translational Modification, Protein Kinase Inhibitors, Proteomics, S, Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors
- {SNA} Bioactive Small Molecule Alphabetical Index, Enzyme Inhibitors,
- {SNA} Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors,
相关文献及参考
- Saklatvala, J., et al., Role for p38 mitogen-activated protein kinase in platelet aggregation caused by collagen or a thromboxane analogue. J. Biol. Chem. 271 , 6586-6589, (1996) 摘要
- Cuenda, A., et al., SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1. FEBS Lett. 364 , 229-233, (1995) 摘要
- Kalmes, A., et al., Raf-1 is activated by the p38 mitogen-activated protein kinase inhibitor SB 203580. FEBS Lett. 444 , 71, (1999) 摘要
- Hall-Jackson, C.A., et al., Effect of SB 203580 on the activity of c-Raf in vitro and in vivo. Oncogene 18 , 2047-2054, (1999) 摘要
- Baldassare, J.J., et al., The role of p38 mitogen-activated protein kinase in IL-1β transcription. J. Immunol. 162 , 5367-5373, (1999) 摘要
- Hashimoto, S., et al., Thioredoxin negatively regulates p38 MAP kinase activation and IL-6 production by tumor necrosis factor-α. Biochem. Biophys. Res. Commun. 258 , 443-447, (1999) 摘要
- Perales M, Mas P, A functional link between rhythmic changes in chromatin structure and the Arabidopsis biological clock. Plant Cell , 2111-23, (2005)
- Brown SE, Szyf M, Epigenetic programming of the rRNA promoter by MBD3. Mol. Cell. Biol. , 4938-52, (2007) 摘要
- Yan J, Gao Z, Yu G, He Q, Weng J, Ye J, Nuclear corepressor is required for inhibition of phosphoenolpyruvate carboxykinase expression by tumor necrosis factor-alpha. Mol. Endocrinol. , 1630-41, (2007) 摘要
- Jacquet S, et. al., The role of RIP2 in p38 MAPK activation in the stressed heart. J. Biol. Chem. , 11964-71, (2008) 摘要
- Sainson RC, et. al., TNF primes endothelial cells for angiogenic sprouting by inducing a tip cell phenotype. Blood , 4997-5007, (2008) 摘要
- Khimji AK, Shao R, Rock
安全信息
GHS Symbol
- H318 Causes serious eye damage 严重伤害眼睛
- H302 Harmful if swallowed 吞食有害
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S39 Wear eye/face protection 戴眼睛/面孔保护装置;
- R22 Harmful if swallowed 吞咽有害
- R41 Risk of serious damage to eyes 有严重损伤眼睛的危险