Conivaptan HCl 盐酸考尼伐坦
CAS 168626-94-6 MFCD00945712
化学结构图
SMILES: Cl.CC1NC2C3=CC=CC=C3N(CCC=2N=1)C(=O)C1C=CC(=CC=1)NC(=O)C1C=CC=CC=1C1C=CC=CC=1
化学属性
| Mol. Formula | C32H27ClN4O2 |
|---|---|
| Mol. Weight | 535.04 |
别名和识别编码
| Chemical Name | Conivaptan HCl |
|---|---|
| CAS Number | 168626-94-6 |
| Synonym | N-[4-[(4,5-Dihydro-2-methylimidazo[4,5-d][1]benzazepin-6(1H)-yl)carbonyl]phenyl]-[1,1'-Biphenyl]-2-carboxamide Hydrochloride Vaprisol YM 087 |
| Chemical Name Translation | 盐酸考尼伐坦 |
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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现货库存
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分类
- Aromatics
- Pharmaceuticals
- Intermediates & Fine Chemicals
产品应用
- Used in treatment of congestive heart failure.
相关文献及参考
- [2]. Fernandez-Varo G, et al. Effect of the V1a/V2-AVP receptor antagonist, Conivaptan, on renal water metabolism and systemic hemodynamics in rats with cirrhosis and ascites. J Hepatol. 2003 Jun;38(6):755-61.
- [3]. Yatsu T, et al. Cardiovascular and renal effects of conivaptan hydrochloride (YM087), a vasopressin V1A and V2 receptor antagonist, in dogs with pacing-induced congestive heart failure. Eur J Pharmacol. 1999 Jul 9;376(3):239-46.
- Arai, Y., et al.: J. Pharm. Sci., 109, 53 (2009),
- Mao, Z., et al.: Clin. Ther., 31, 1542 (2009),
- [1]. Wada K, et al. Intravenous administration of conivaptan hydrochloride improves cardiac hemodynamics in rats with myocardial infarction-induced congestive heart failure.
- [1]. Wada K, et al. Intravenous administration of conivaptan hydrochloride improves cardiac hemodynamics in rats with myocardial infarction-induced congestive heart failure. Eur J Pharmacol. 2005 Jan 10;507(1-3):145-51. Epub 2005 Jan 1.
