N-(3-Fluoro-5-(Pyridin-3-Yl)Phenyl)-5-Methoxy-6-(Trifluoromethyl)Indoline-1-Carboxamide 化合物SB228357
CAS 181629-93-6 MFCD00950378
化学结构图
SMILES: COC1=CC2CCN(C(=O)NC3C=C(F)C=C(C=3)C3C=NC=CC=3)C=2C=C1C(F)(F)F
化学属性
| Mol. Formula | C22H17F4N3O2 |
|---|---|
| Mol. Weight | 431.38 |
别名和识别编码
| Chemical Name | N-(3-Fluoro-5-(Pyridin-3-Yl)Phenyl)-5-Methoxy-6-(Trifluoromethyl)Indoline-1-Carboxamide |
|---|---|
| Synonym | N-[3-Fluoro-5-(3-pyridinyl)phenyl]-2,3-dihydro-5-methoxy-6-(trifluoromethyl)-1H-indole-1-carboxamide |
| MDL Number | MFCD00950378 |
| Chemical Name Translation | 化合物SB228357 |
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分类
- {SNA} Antagonists, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Neuroscience, Neurotransmission, Neurotransmitters, S, Serotonergics
相关文献及参考
- [2]. Reavill C, et al. Attenuation of haloperidol-induced catalepsy by a 5-HT2C receptor antagonist. Br J Pharmacol. 1999 Feb;126(3):572-4.
- [1]. Bromidge SM, et al. Biarylcarbamoylindolines are novel and selective 5-HT(2C) receptor inverse agonists: identification of 5-methyl-1-[[2-[(2-methyl-3-pyridyl)oxy]- 5-pyridyl]carbamoyl]-6-trifluoromethylindoline (SB-243213) as a potential antidepressant/anxiolytic agent. J Med Chem. 2000 Mar 23;43(6):1123-34.
- [1]. Bromidge SM, et al. Biarylcarbamoylindolines are novel and selective 5-HT(2C) receptor inverse agonists: identification of 5-methyl-1-[[2-[(2-methyl-3-pyridyl)oxy]- 5-pyridyl]carbamoyl]-6-trifluoromethylindoline (SB-243213) as a potential antidepressant/anxiolytic agent. J Med Chem. 2000 Mar 23;43(6):1123-34.
- [2]. Reavill C, et al. Attenuation of haloperidol-induced catalepsy by a 5-HT2C receptor antagonist. Br J Pharmacol. 1999 Feb;126(3):572-4.
