Oseltamivir Acid 奥斯他伟酸
CAS 187227-45-8 MFCD00953940
化学结构图
SMILES: CC(=O)N[C@@H]1[C@@H](N)CC(=C[C@H]1OC(CC)CC)C(O)=O |&1:4,5,10|
化学属性
| Mol. Formula | C14H24N2O4 |
|---|---|
| Mol. Weight | 284 |
别名和识别编码
| Chemical Name | Oseltamivir Acid |
|---|---|
| CAS Number | 187227-45-8 |
| Synonym | (3R,4R,5S)- |
| Chemical Name Translation | 奥斯他伟酸 |
| MDL Number |
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资金保障
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分类
- Amines
- Metabolites & Impurities
- Pharmaceuticals
- Intermediates & Fine Chemicals
产品应用
- A metabolite of Oseltamivir.
相关文献及参考
- [2]. Ghosh GC, et al. Oseltamivir carboxylate, the active metabolite of oseltamivir phosphate (Tamiflu), detected in sewage discharge and river water in Japan. Environ Health Perspect. 2010 Jan;118(1):103-7.
- [3]. Ferraris O, et al. Sensitivity of influenza viruses to zanamivir and oseltamivir: a study performed on viruses circulating in France prior to the introduction of neuraminidase inhibitors in clinical practice. Antiviral Res. 2005 Oct;68(1):43-8.
- [4]. Gubareva LV, et al. Comparison of the activities of zanamivir, oseltamivir, and RWJ-270201 against clinical isolates of influenza virus and neuraminidase inhibitor-resistant variants.Antimicrob Agents Chemother. 2001 Dec;45(12):3403-8.
- [5]. Yen HL, et al. Virulence may determine the necessary duration and dosage of oseltamivir treatment for highly pathogenic A/Vietnam/1203/04 influenza virus in mice. J Infect Dis. 2005 Aug 15;192(4):665-72.
- [6]. Hoffmann G, et al. Nonclinical pharmaco
