N-Boc-4-(Fmoc-Amino)Piperidine-4-Carboxylic Acid 1-(N-Boc)-4-(N-FMOC-氨基)-4-哌啶甲酸
CAS 183673-66-7 MFCD01318741
化学结构图
SMILES: CC(C)(C)OC(=O)N1CCC(CC1)(NC(=O)OCC1C2C=CC=CC=2C2C=CC=CC=21)C(O)=O
化学属性
| Mol. Formula | C26H30N2O6 |
|---|---|
| Mol. Weight | 466.53 |
别名和识别编码
| Chemical Name | N-Boc-4-(Fmoc-Amino)Piperidine-4-Carboxylic Acid |
|---|---|
| CAS Number | 183673-66-7 |
| Synonym | 1-(tert-Butoxycarbonyl)-4-[[[(9H-fluoren-9-yl)methoxy]carbonyl]amino]piperidine-4-carboxylic Ac Fmoc-L-Pip(Boc)-OH, 1-Boc-4-Fmoc-Pip-OH Fmoc-L-Pip(Boc)-OH, 1-Boc-4-Fmoc-Pip-OH N-Boc-4-(Fmoc-氨基)哌啶-4-羧酸 |
| MDL Number | MFCD01318741 |
| PubChem Substance ID | 57653419 |
| Beilstein Registry Number | 7609053 |
| Chemical Name Translation | 1-(N-Boc)-4-(N-FMOC-氨基)-4-哌啶甲酸 |
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分类
- Amino Acids & Derivatives
- Heterocycles
- {SNA} Chemical Biology, Chemical Synthesis, Others, Peptide Chemistry, Unnatural Amino Acid Derivatives
- Pharmaceuticals
- {SNA} Chemical Biology, Chemical Synthesis, Other Unnatural Amino Acids & Derivatives, Peptide Chemistry, Unnatural Amino Acids & Derivatives
- Intermediates & Fine Chemicals
产品应用
- N-Boc-amino-(4-N-Fmoc-piperidinyl)carboxylic acid is used in the preparation of synthetic peptide amides as kappa opioid receptor agonists for treatment of pain, pruritis and inflammation associated w
相关文献及参考
- Ghosh, S., et al.: J. Med. Chem., 49, 2669 (2006),
安全信息
GHS Symbol
- P281 Use personal protective equipment as required. 使用所需的个人防护装备。
- P305+P351+P338
- P313 Get medical advice/attention. 获取医疗咨询/就医
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S37 Wear suitable gloves 戴适当手套；
- S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
