CAS 66794-74-9 MFCD01667688-Encainide hydrochloride Encainide 盐酸盐 TAO{mole}

Mol. Formula	C22H28N2O2· HCl
Mol. Weight	388.93

Chemical Name	Encainide hydrochloride
Synonym	(+/-)-4-Methoxy-N-[2-[2-(1-methyl-2-piperidinyl)ethyl]phenyl]benzamide 盐酸盐 MJ-9067 Enkade Encainide hydrochloride 4-Methoxy-2'-(2-(1-methyl-2-piperidyl)ethyl)benzanilide hydrochloride Enkaid Encainide 盐酸盐
MDL Number	MFCD01667688
CAS Number	66794-74-9
Chemical Name Translation	Encainide 盐酸盐
PubChem Substance ID	329799083

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分类

{SNA} Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bristol-Myers Squibb, E, Ion Channels, Monovalent Ion Channels, Other Sodium Channel Modulators, Sodium Channel Modulators, Voltage-gated Ion Channels, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
{SNA} Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Bristol-Myers Squibb, Cell Biology, Cell Signaling and Neuroscience, E, Ion Channels, Monovalent Ion Channels, Other Sodium Channel Modulators, Sodium Channel Modulators, Voltage-gated Ion Channels

安全信息

GHS Symbol

WGK Germany3

Precautionary statements

P301+P310
P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P305+P351+P338

Hazard statements

H315 Causes skin irritation 会刺激皮肤
H319 Causes serious eye irritation 严重刺激眼睛
H301 Toxic if swallowed 吞食有毒
H335 May cause respiratory irritation 可能导致呼吸道刺激

RTECSCV5521500

Signal word Danger

Personal Protective Equipment Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Safety Statements

S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；

Hazard Codes T

Risk Statements

R25 Toxic if swallowed 吞咽有毒
R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 86 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NDADD8 New Drugs Annual: Cardiovascular Drugs.  (New York, NY)  V.1-2,
   1983-84.  For publisher information, see NCDREP.  Volume(issue)/page/year:
   1,93,1983

{haz

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 5500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NDADD8 New Drugs Annual: Cardiovascular Drugs.  (New York, NY)  V.1-2,
   1983-84.  For publisher information, see NCDREP.  Volume(issue)/page/year:
   1,93,1983

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 57 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NDADD8 New Drugs Annual: Cardiovascular Drugs.  (New York, NY)  V.1-2,
   1983-84.  For publisher information, see NCDREP.  Volume(issue)/page/year:
   1,93,1983

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 43 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NDADD8 New Drugs Annual: Cardiovascular Drugs.  (New York, NY)  V.1-2,
   1983-84.  For publisher information, see NCDREP.  Volume(issue)/page/year:
   1,93,19

Encainide hydrochloride Encainide 盐酸盐

CAS 66794-74-9 MFCD01667688

化学结构图

化学属性

别名和识别编码

分类

安全信息

系列性分类

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