Tropisetron 托烷司琼
CAS 89565-68-4 MFCD01680536
化学结构图
SMILES: Cl.CCOC(=O)C1=C(N)SC2CN(CC3C=CC=CC=3)CCC=21
化学属性
| Mol. Formula | C17H20N2O2S.ClH |
|---|---|
| Mol. Weight | 352.884 |
别名和识别编码
| Chemical Name | Tropisetron |
|---|---|
| Chemical Name Translation | 托烷司琼 |
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相关文献及参考
- Bioorg Med Chem Lett. 2001 Feb 12;11(3):319-21.
- [2]. Vega Lde L, et al. The 5-HT3 receptor antagonist tropisetron inhibits T cell activation by targeting the calcineurin pathway. Biochem Pharmacol. 2005 Aug 1;70(3):369-80.
- [3]. Stratz C, et al. The anti-inflammatory effects of the 5-HT? receptor antagonist tropisetron are mediated by the inhibition of p38 MAPK activation in primary human monocytes. Int Immunopharmacol. 2012 Aug;13(4):398-402.
- [4]. Candelario-Jalil E, et al. Detrimental effects of tropisetron on permanent ischemic stroke in the rat. BMC Neurosci. 2008 Feb 6;9:19.
- Bioorg Med Chem Lett. 2001 Feb 12;11(3):319-21.
- [1]. Macor JE, et al. The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective alpha7 nicotinic receptor partial agonist.
- [1]. Macor JE, et al. The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective alpha7 nicotinic receptor partial agonist.
- [2]. Vega Lde L, et a
