2(1H)-Quinoxalinone,1-(2-diethylamino)ethyl-3-(4-methoxybenzyl)-,hydrochloride
CAS 55750-05-5 MFCD01684929
化学结构图
SMILES: Cl.COC1C=CC(CC2=NC3C=CC=CC=3N(CCN(CC)CC)C2=O)=CC=1
化学属性
| Mol. Formula | C22H28ClN3O2 |
|---|---|
| Mol. Weight | 401.93 |
别名和识别编码
| Chemical Name | Caroverine hydrochloride |
|---|---|
| Synonym | 1-(2-Diethylamino)ethyl-3-((4-methoxyphenyl)methyl)-2(1H)-quinoxalinone 1-Diethylaminoethyl-3-(p-methoxybenzyl)-2-quinoxaone hydrochloride 1-[2-(Diethylamino)ethyl]-3-[(4-methoxyphenyl)methyl]-2(1H)-quinoxalinone monohydrochloride Caroverine hydrochloride |
| MDL Number | MFCD01684929 |
| Wiswesser Line Notation | T66 BKV DNJ B2N2&2 D1R DO1 &GH |
| CAS Number | 55750-05-5 |
| PubChem Substance ID | 329774856 |
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分类
- {SNA} AMPA/Kainate Antagonists, Bioactive Small Molecules, C-CH, Cell Biology, Cell Signaling and Neuroscience, Excitatory Amino Acids, Neuroscience, Neurotransmission, Neurotransmitters
- {SNA} AMPA/Kainate Antagonists, Bioactive Small Molecule Alphabetical Index, C-CH, Excitatory Amino Acids, Neuroscience, Neurotransmission, Neurotransmitters, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学
安全信息
GHS Symbol
- H302 Harmful if swallowed 吞食有害
- R22 Harmful if swallowed 吞咽有害
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 172 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - other changes REFERENCE : OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 4,233,1970
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 900 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - other changes REFERENCE : OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 4,233,1970
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 49 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - other changes REFERENCE : OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 4,233,1970
