1-NITRO-9-(3-HEXYLAMINOPROPYLAMINO)ACRIDINE DIHYDROCHLORIDE

CAS 77280-91-2 MFCD01698302

化学结构图

77280-91-2
SMILES: Cl.Cl.CCCCCCNCCCNC1=C2C(C=CC=C2[N+]([O-])=O)=NC2C=CC=CC=21

化学属性

Mol. FormulaC22H28N4O2.2ClH
Mol. Weight453.46

别名和识别编码

Chemical Name1,3-Propanediamine,N-hexyl-N'-(1-nitro-9-acridinyl)-, dihydrochloride
Wiswesser Line NotationT C666 BNJ GNW IM3M6 &GH 2
Synonym 9-((3-(Hexylamino)propyl)amino)-1-nitroacridine dihydrochloride C 1006 1-Nitro-9-(3-hexylaminopropylamino)acridine dihydrochloride Acridine, 9-((3-(hexylamino)propyl)amino)-1-nitro-, dihydrochloride
CAS Number77280-91-2
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安全信息

RTECSTX8040000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3820 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
   1001, 00-068 Warsaw 1, Poland)  V.10-    1962-  Volume(issue)/page/year:
   30,385,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Bird - pigeon
DOSE/DURATION           : 10500 ug/kg
TOXIC EFFECTS :
   Gastrointestinal - nausea or vomiting
REFERENCE :
   AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB
   1001, 00-068 Warsaw 1, Poland)  V.10-    1962-  Volume(issue)/page/year:
   28,777,1980

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Human HeLa cell
DOSE/DURATION           : 2500 nmol/L
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   49,311,1984

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Human HeLa cell
DOSE/DURATION           : 1 umol/L
REFERENCE :
   CBINA8 Chemico-Biological Interactions.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1969-  Volume(issue)/page/year:
   49,311,1984

TYPE OF TEST            : Host-mediated assay
TEST SYSTEM             : Rodent - mouse HeLa cell
DOSE/DURATION           : 44 mg/kg
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   38,1301,1989

系列性分类


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