1-Aminopiperidine Hydrochloride N-氨基哌啶盐酸盐
CAS 63234-70-8 MFCD01701508
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            分类
- Amines
 - Heterocycles
 - Metabolites & Impurities
 - Pharmaceuticals
 - Intermediates & Fine Chemicals
 
产品应用
- 1-Aminopiperidine is a metabolite (M1) of the canabinoid receptor 1 antagonist Rimonabant (R517800), an antiobesity agent.
 
相关文献及参考
- Hillard, C., et al.: J. Neurochem., 69, 631 (1997),
 - Bisogno, T., et al.: J. Biol. Chem., 272, 3315 (1997),
 - Di Marzo, V., et al.: Life Sci., 65, 645 (1999),
 
安全信息
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
 - S37 Wear suitable gloves 戴适当手套;
 
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
 
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 400 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ABMGAJ Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.) V.1-41, 1958-82. For publisher information, see BBIADT. Volume(issue)/page/year: 17,614,1966
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 330 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ABMGAJ Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.) V.1-41, 1958-82. For publisher information, see BBIADT. Volume(issue)/page/year: 17,614,1966
