N-NITROSO-2-METHOXY-2,6-DIMETHYLMORPHOLINE
CAS 73239-98-2 MFCD01713924
化学结构图
SMILES: COC1(C)CN(CC(C)O1)N=O
化学属性
| Mol. Formula | C7H14N2O3 |
|---|---|
| Mol. Weight | 174.23 |
别名和识别编码
| Chemical Name | Morpholine, 2,6-dimethyl-2-methoxy-N-nitroso- |
|---|---|
| Wiswesser Line Notation | T6N DOTJ ANO CO1 C1 E1 |
| Synonym | Morpholine, 2,6-dimethyl-2-methoxy-4-nitroso- N-Nitroso-2-methoxy-2,6-dimethylmorpholine |
| CAS Number | 73239-98-2 |
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安全信息
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Parenteral SPECIES OBSERVED : Rodent - hamster DOSE/DURATION : 50 mg/kg TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors Liver - tumors REFERENCE : CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 13,233,1981
TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Parenteral SPECIES OBSERVED : Rodent - hamster DOSE/DURATION : 250 mg/kg TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors REFERENCE : CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 13,233,1981
TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Parenteral SPECIES OBSERVED : Rodent - hamster DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - other changes Liver - other changes Blood - hemorrhage REFERENCE : CALEDQ Cancer Letters (Shannon, Ireland). (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1975- Volume(issue)/page/year: 13,233,1981
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 200 nmol/plate REFERENCE : JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 64,157,1980
