CAS 2182-14-1 MFCD01744432-Vindoline 文多灵 TAO{mole}

Vindoline 文多灵

CAS 2182-14-1 MFCD01744432

化学结构图

SMILES: CCC12C=CCN3CCC4(c5ccc(OC)cc5N(C)C4C(O)(C(=O)OC)C1OC(C)=O)C32

化学属性

Mol. Formula	C25 H32 N2 O6
Mol. Weight	456.53
Density	1.33
Melting Point	162-1640C
Boiling Point
Flash Point	-

别名和识别编码

Chemical Name	Vindoline
CAS Number	2182-14-1
Synonym	(-)-Vindoline (2?,3?,4?,5?,12?,19?)-4-(Acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy-1-methyl-aspidospermidine-3-carboxylic Acid Methyl Ester (2beta,3beta,4beta,5alpha,12beta,19alpha)-4-(Acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy-1-methyl-aspidospermidine-3-carboxylic acid methyl ester Methyl (2β,3β,4β,5α,12R,19α)-4-(Acetyloxy)-6,7-didehydro-3-hydroxy-16-methoxy-1-methylaspidospermidine-3-carboxylate NSC 91994 Vindolin Vindoline {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}
MDL Number	-
EC Number	218-558-0
Chemical Name Translation	文多灵
Wiswesser Line Notation	T C6 B5665 2AB S BX IN QN NU JH&&TTTJ FO1 I1 KVO1 KQLOV1 M2
PubChem Substance ID	260535
InChI	InChI=1S/C25H32N2O6/c1-6-23-10-7-12-27-13-11-24(19(23)27)17-9-8-16(31-4)14-18(17)26(3)20(24)25(30,22(29)32-5)21(23)33-15(2)28/h7-10,14,19-21,30H,6,11-13H2,1-5H3/t19-,20+,21+,23+,24+,25-/m0/s1
LabNetwork Molecule ID	LN01326585
Canonical SMILES	CC[C@]12C=CCN3CC[C@]4([C@@H]13)[C@H](N(C)c5cc(OC)ccc45)[C@@](O)([C@H]2OC(=O)C)C(=O)OC

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产品应用

A novel antitumor agent.

安全信息

Storage condition -20 -20°C -20℃ 2-8°C 2-8°C, protect from light 储存温度 2-8°C

GHS Symbol

WGK Germany3

Precautionary statements

P201 Obtain special instructions before use. 使用前获取专门指示。
P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
P203
P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P281 Use personal protective equipment as required. 使用所需的个人防护装备。
P308+P313
P318
P405 Store locked up. 上锁保管。
P501 Dispose of contents/container to..… 处理内容物/容器.....

Hazard statements

H341 Suspected of causing genetic defects 怀疑导致遗传性缺陷

RTECSCJ0120000

Signal word Warning

Safety Statements

S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；

Hazard Codes Xn

Risk Statements

R68 Possible risk of irreversible effects 可能有不可挽回的作用的危险

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - excitement
REFERENCE :
   33GVAL "Catharanthus Alkaloids," Taylor, W.I., and N.R. Farnsworth, eds.,
   New York, Marcel Dekker, 1975  Volume(issue)/page/year: -,73,1975