Emamectin benzoate 甲胺基阿维菌素苯甲酸盐
CAS 155569-91-8 MFCD01757274
化学结构图
SMILES: CC[C@H](C)[C@H]1O[C@@]2(C[C@@H]3C[C@@H](CC=C(C)[C@@H](O[C@H]4C[C@H](OC)[C@@H](O[C@H]5C[C@H](OC)[C@@H](NC)[C@H](C)O5)[C@H](C)O4)[C@@H](C)C=CC=C4CO[C@@H]5[C@H](O)C(C)=C[C@@H](C(=O)O3)[C@]45O)O2)C=C[C@@H]1C.OC(=O)C1C=CC=CC=1 |c:12,52,65,73,75,t:42,77|
别名和识别编码
| Synonym | 甲氨基阿维菌素苯甲酸盐 (4″R)-4″-去氧-4″-(甲氨基)阿维菌素 B1 苯甲酸盐 MK 244 Emamectin benzoate MK 0244 |
|---|---|
| MDL Number | MFCD01757274 |
| Chemical Name | Emamectin benzoate |
| Chemical Name Translation | 甲胺基阿维菌素苯甲酸盐 |
| CAS Number | 155569-91-8 |
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相关文献及参考
- [2]. Shaorong Luan, et al. Emamectin benzoate induces ROS-mediated DNA damage and apoptosis in Trichoplusia Tn5B1-4 cells. Chem Biol Interact. 2017 Aug 1;273:90-98.
- [3]. Özge Temiz, et al. Biopesticide emamectin benzoate in the liver of male mice: evaluation of oxidative toxicity with stress protein, DNA oxidation, and apoptosis biomarkers. Environ Sci Pollut Res Int. 2020 Jun;27(18):23199-23205.
- [1]. Chenguang Niu, et al. Toxic effects of the Emamectin Benzoate exposure on cultured human bronchial epithelial (16HBE) cells. Environ Pollut. 2020 Feb;257:113618.
- [1]. Chenguang Niu, et al. Toxic effects of the Emamectin Benzoate exposure on cultured human bronchial epithelial (16HBE) cells. Environ Pollut. 2020 Feb;257:113618.
- [2]. Shaorong Luan, et al. Emamectin benzoate induces ROS-mediated DNA damage and apoptosis in Trichoplusia Tn5B1-4 cells. Chem Biol Interact. 2017 Aug 1;273:90-98.
- [3]. Özge Temiz, et al. Biopesticide emamectin ben
安全信息
GHS Symbol
- P301+P310
- P273 Avoid release to the environment. 避免释放到环境中。
- P305+P351+P338
- H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
- H319 Causes serious eye irritation 严重刺激眼睛
- H301 Toxic if swallowed 吞食有毒
- S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
- R25 Toxic if swallowed 吞咽有毒
- R21 Harmful in contact with skin 与皮肤接触有害
- R23 Toxic by inhalation 吸入有毒
- R57 Toxic to bees 对蜜蜂有毒
- R36 Irritating to eyes 刺激眼睛
- R50/53
- R58 May cause long-term adverse effects in the environment 对环境可能导致长期有害的作用
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE : 105 mg/kg
SEX/DURATION : female 6-21 day(s) after conception
lactating female 21 day(s) post-birth
TOXIC EFFECTS :
Reproductive - Maternal Effects - other effects
Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight
gain)
Reproductive - Effects on Newborn - behavioral
REFERENCE :
NETEEC Neurotoxicology and Teratology. (Pergamon Press Inc., Maxwell House,
Fairview Park, Elmsford, NY 10523) V.9- 1987- Volume(issue)/page/year:
19,315,1997