(E)-6-(3,4-DiHydroxystyryl)-4-Hydroxy-2H-Pyran-2-One (E)-6-(3,4-二羟基苯乙烯基)-4-羟基-2H-吡喃-2-酮

CAS 555-55-5 MFCD01866972

化学结构图

555-55-5
SMILES: O=c1cc(O)cc(C=Cc2ccc(O)c(O)c2)o1

化学属性

Mol. Weight246.22
Mol. FormulaC13H10O5
Melting Point312-315 ºC
Density1.657

别名和识别编码

Synonym 6-(3,4-dihydroxystyrl)-4-hydroxy-2-pyrone 6-[(1E)-2-(3,4-Dihydroxyphenyl)ethenyl]-4-hydroxy-2H-pyran-2-one; 6-(3,4-Dihydroxystyryl)-4-hydroxy-2H-pyran-2-one; (E)-6-[2-(3,4-Dihydroxyphenyl)ethenyl]-4-hydroxy-2H-pyran-2-one; 6-(3,4-Dihydroxystyryl)-4-hydroxy-2-pyrone
MDL NumberMFCD01866972
PubChem Substance ID54685921
CAS Number555-55-5
Chemical Name(E)-6-(3,4-DiHydroxystyryl)-4-Hydroxy-2H-Pyran-2-One
Chemical Name Translation(E)-6-(3,4-二羟基苯乙烯基)-4-羟基-2H-吡喃-2-酮
InChIKeySGJNQVTUYXCBKH-HNQUOIGGSA-N
InChIInChI=1S/C13H10O5/c14-9-6-10(18-13(17)7-9)3-1-8-2-4-11(15)12(16)5-8/h1-7,14-16H/b3-1+
LabNetwork Molecule IDLN04681775
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分类

  • {SNA} Antitumor Agents,
  • {SNA} Antitumor Agents, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, H, Kinase/Phosphatase Biology, P to Q, Protein Kinase C (PKC), Protein Kinase C beta, Protein Kinase Inhibitors, Protein kinase C, Serine/Threonine Kinase Biology, Serine/Threonine Kinase Inhibitors, 癌症研究
  • {SNA} Bioactive Small Molecule Alphabetical Index, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, H, Kinase/Phosphatase Biology, P to Q,

相关文献及参考

  • Gonindard, C., et al., Synthetic hispidin, a PKC inhibitor, is more cytotoxic toward cancer cells than normal cells in vitro. Cell Biol. Toxicol. 13 , 141-153, (1997) 摘要
  • [1]. Kim DE, et al. The protective effect of hispidin against hydrogen peroxide-induced apoptosis in H9c2 cardiomyoblast cells through Akt/GSK-3β and ERK1/2 signaling pathway. Exp Cell Res. 2014 Oct 1;327(2):264-75.

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类


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