RHIZOXIN
CAS 90996-54-6 MFCD01939948
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分类
- {SNA} Antibiotics, Antibiotics A to Z, Antibiotics N-S, Antitumor Agents, Bioactive Small Molecules, Cancer Research, Cell Biology, Cell Signaling and Neuroscience, Cytoskeleton and Extracellular Matrix, Microtobule Inhibitors, Microtubule Inhibitors, R
安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 3700 ug/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) Behavioral - ataxia Skin and Appendages - hair REFERENCE : ANONE2 Annals of Oncology. (European Society for Medical Oncology, Distributed by Kluwer Academic Publishers, Postbus 17, 3300 AA Dordrecht, Netherlands) V.1- 1990- Volume(issue)/page/year: 3,755,1992
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2500 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 39,762,1986
TYPE OF TEST : DNA inhibition TEST SYSTEM : Non-mammalian species Embryo DOSE/DURATION : 16 umol/L REFERENCE : JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 40,66,1987