3-Fluoro-4-Formylphenylboronic Acid 3-氟-4-醛基苯硼酸

CAS 248270-25-9 MFCD02093051

化学结构图

248270-25-9
SMILES: OB(O)C1C=C(F)C(C=O)=CC=1

化学属性

Mol. FormulaC7H6BFO3
Mol. Weight167.93
Melting Pointca 240°
TSCANo

别名和识别编码

Chemical Name3-Fluoro-4-Formylphenylboronic Acid
CAS Number248270-25-9
Alfabeta NameFLUOROFORMYLPHENYLBORONICACID 34---
MDL NumberMFCD02093051
Synonym 3-氟-4-醛基苯硼酸 4-Borono-3-fluorobenzaldehyde3-Fluoro-4-formylphenylboronic acid 4-Borono-3-fluorobenzaldehyde
PubChem Substance ID253661465
EC Number000-000-0
Chemical Name Translation3-氟-4-醛基苯硼酸
Reaxys-RN11110121
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分类

  • {SNA} Aldehydes, Aryl Boronic Acids, Boronic Acids, Boronic Acids and Derivatives, Building Blocks, C7, Carbonyl Compounds, Chemical Synthesis, Disubstituted Aryl Boronic Acids, Organic Building Blocks, Organometallic Reagents
  • Aldehydes, Aryl Boronic Acids, Boronic Acids, Boronic Acids and Derivatives, Building Blocks, C7, Carbonyl Compounds, Chemical Synthesis, Disubstituted Aryl Boronic Acids, Organic Building Blocks, Organometallic Reagents

相关文献及参考

  • 1. Grob, J. E.; et al., One-pot reductive amination and Suzuki-Miyaura cross-coupling of formyl aryl and heteroaryl MIDA boronates in array format J. Org. Chem. 76 , 4930-4940, (2011)
  • 2. Apsel, B.; et al., Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases Nature Chem. Biol. 4 , 691-699, (2008)

安全信息

Warnings IRRITANT
WGK Germany3
GHS Symbol
Precautionary statements
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+P351+P338+P337+P313
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Signal word
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Hazard Codes Xi
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S37 Wear suitable gloves 戴适当手套;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类


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