CAS 65678-07-1 MFCD02179365-AG1024 2-(3-溴-5-(叔丁基)-4-羟基亚苄基)丙二腈 TAO{mole}

SMILES: CC(C)(C)c1cc(C=C(C#N)C#N)cc(Br)c1O

Chemical Name	AG1024
MDL Number	MFCD02179365
Chemical Name Translation	2-(3-溴-5-(叔丁基)-4-羟基亚苄基)丙二腈
Formula	C14H13BrN2O
Synonym	AG1024; AG-1024; AG 1024. Tyrphostin.
IUPAC Name	2-(3-bromo-5-tert-butyl-4-hydroxybenzylidene)malononitrile
InChIKey	ABBADGFSRBWENF-UHFFFAOYSA-N
InChI	InChI=1S/C14H13BrN2O/c1-14(2,3)11-5-9(4-10(7-16)8-17)6-12(15)13(11)18/h4-6,18H,1-3H3
Canonical SMILES	N#C/C(C#N)=C/C1=CC(C(C)(C)C)=C(O)C(Br)=C1
CAS Number	65678-07-1

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

{SNA} Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Insulin-Like Growth Factor Receptor (IGF1R and IGf2R), Kinase/Phosphatase Biology, P to Q, Protein Kinase Inhibitors, Protein kinase, tyrosine, EGF receptor, Receptor Tyrosine Kinase Biology, Receptor Tyrosine Kinase Inhibitors

AG-1024 is also called Tyrphostin, is a selective inhibitor of IGF-1R. AG-1024 was used to evaluate effects on proliferation, radiosensitivity, and radiation-induced cell apoptosis in a human breast cancer cell line MCF-7. Exposure to Tyrphostin AG 1024 inhibited proliferation and induced apoptosis in a time-dependent manner, and the degree of growth inhibition for IC20 plus irradiation (4 Gy) was up to 50% compared to the control. Tyrphostin AG 1024 could be used as a potential therapeutic agent in combination with irradiation.

WGK Germany3

Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

Storage condition Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

相关产品推荐