3-(N-Methylaminocarbonyl)Phenylboronic Acid 3-(N-甲基甲酰氨)苯基硼酸

CAS 832695-88-2 MFCD04038918

化学结构图

832695-88-2
SMILES: CNC(=O)C1=CC(=CC=C1)B(O)O

化学属性

Mol. FormulaC8H10BNO3
Mol. Weight178.98
Melting Point114-124°
TSCANo

别名和识别编码

Chemical Name3-(N-Methylaminocarbonyl)Phenylboronic Acid
CAS Number832695-88-2
Synonym 3-(Methylaminocarbonyl)phenylboronic acid 3-(Methylcarbamoyl)phenylboronic Acid 3-(N-Methylaminocarbonyl)benzeneboronic acid B-[3-[(Methylamino)carbonyl]phenyl]boronic Acid [3-(Methylaminocarbonyl)phenyl]boronic Acid [3-(N-Methylaminocarbonyl)
MDL NumberMFCD04038918
Chemical Name Translation3-(N-甲基甲酰氨)苯基硼酸
PubChem Substance ID329781734
LabNetwork Molecule IDLN00005036
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分类

  • Amines
  • Aromatics
  • Boron Derivatives
  • {SNA} Aryl Boronic Acids, Boronic Acids, Boronic Acids and Derivatives, Chemical Synthesis, Monosubstituted Aryl Boronic Acids, Organometallic Reagents

产品应用

  • Used in the preparation of thiazolopyridinylacetamide derivatives and analogs for use as PI3K and mTOR kinase inhibitors.

相关文献及参考

  • Arai, Y., et al.: Curr. Opin. Pharmacol., 7, 124 (2007),
  • Ashwell, M., et al.: Bioorg. Med. Chem. Lett., 10, 783 (2000),
  • Decaux, G., et al.: Lancet, 371, 1624 (2008),

安全信息

Safety Statements
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S37 Wear suitable gloves 戴适当手套;
  • S39 Wear eye/face protection 戴眼睛/面孔保护装置;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
  • R37/38 Irritating to respiratory system and skin 对呼吸系统和皮肤有刺激性
  • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
  • R22 Harmful if swallowed 吞咽有害
  • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
GHS Symbol
WGK Germany3
Precautionary statements
  • P305+P351+P338+P310
  • P301+P312+P330
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H318 Causes serious eye damage 严重伤害眼睛
  • H302 Harmful if swallowed 吞食有害
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
Signal word Danger
Hazard Codes Xn

系列性分类


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