(S)-2-(Butylsulfonamido)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)propanoic acid (S)-2-(丁基磺酰胺)-3-(4-(4-(哌啶-4-基)丁氧基)苯基)丙酸
CAS 144494-65-5 MFCD05237246
化学结构图
SMILES: CCCCS(=O)(=O)N[C@@H](CC1C=CC(=CC=1)OCCCCC1CCNCC1)C(O)=O
化学属性
| Mol. Formula | C22H36N2O5S |
|---|---|
| Mol. Weight | 440.60 |
别名和识别编码
| Chemical Name | (S)-2-(Butylsulfonamido)-3-(4-(4-(piperidin-4-yl)butoxy)phenyl)propanoic acid |
|---|---|
| Synonym | (2S)-2-(Butylsulfonylamino)-3-{4-[4-(4-piperidyl)butoxy}phenyl propanoic acid N-(Butylsulfonyl)-O-[4-(4-piperidinyl)butyl]-L-tyrosine |
| MDL Number | MFCD05237246 |
| Beilstein Registry Number | 6182267 |
| Chemical Name Translation | (S)-2-(丁基磺酰胺)-3-(4-(4-(哌啶-4-基)丁氧基)苯基)丙酸 |
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相关文献及参考
- [2]. van 't Hof AW, Valgimigli M. Defining the role of platelet glycoprotein receptor inhibitors in STEMI: focus on tirofiban. Drugs. 2009;69(1):85-100.
- [3]. Valgimigli M, Biondi-Zoccai G, Tebaldi M et al. Tirofiban as adjunctive therapy for acute coronary syndromes and percutaneous coronary intervention: a meta-analysis of randomized trials. Eur Heart J. 2010 Jan;31(1):35-49.
- [4]. Valgimigli M, Tebaldi M. Safety evaluation of tirofiban. Expert Opin Drug Saf. 2010 Sep;9(5):801-19.
- [5]. Diaz JF, Cardenal R, Gomez-Manchero A, Sanchez-Gonzalez C. Safety and efficacy of tirofiban as adjunctive therapy for patients with ST-elevation myocardial infarction: a comparison versus placebo and abciximab. Cardiovasc Hematol Agents Med Chem. 2011 Jul 1;9(3):147-53.
- [1]. Winter JP, Juergens
- [1]. Winter JP, Juergens CP. The role of tirofiban in the management of coronary artery disease. Cardiovasc Hematol Disord Drug Targets. 2008 Jun;8(2):138-46.
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
