3-(1-METHYL-4-PHENYLACETYL-1H-2-PYRROLYL)-N-HYDROXY-2-PROPENAMIDE
CAS 676599-90-9 MFCD05865226
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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分类
- AN-AZ, Bioactive Small Molecules, Bioactive Small Molecules for Epigenetic Research, Biochemicals and Reagents, Cell Biology, D to K, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, Epigenetics, Histone Deacetylase Inhibitors, Histone deacetylase, Molecular Biology, Other HDAC Inhibitors
- {SNA} Bioactive Small Molecules for Epigenetic Research, D to K, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Histone Deacetylase Inhibitors, Histone deacetylase, Other HDAC Inhibitors, 分子生物学, 生化试剂, 表观遗传学, 酶、抑制剂和底物
相关文献及参考
- 1. Mai, A., et al., Novel uracil-based 2-aminoanilide and 2-aminoanilide-like derivatives: histone deacetylase inhibition and in-cell activities Bioorg. Med. Chem. Lett. 18 , 2530-2535, (2008)
- Mai, A., et al., 3-(4-Aroyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-alkylamides as a new class of synthetic histone deacetylase inhibitors. J. Med. Chem. 46 , 512-524, (2003) 摘要
- Mai, A., et al., Binding Mode Analysis of 3-(4-benzoyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamide: A new synthetic histone deacetylase inhibitor inducing histone hyperacetylation, growth inhibition, and terminal cell differentiation. J. Med. Chem. 45 , 1778-1784, (2002)
- Massa, S., et al., 3-(4-Aroyl-1H-pyrrol-2-yl)-N-hydroxy-2-propenamides, a new class of synthetic histone deacetylase inhibitors. J. Med. Chem. 44 , 2069-2072, (2001)
安全信息
GHS Symbol


- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- H317 May cause an allergic skin reaction 可能导致皮肤过敏
- H318 Causes serious eye damage 严重伤害眼睛
- H302 Harmful if swallowed 吞食有害
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
- R22 Harmful if swallowed 吞咽有害
- R41 Risk of serious damage to eyes 有严重损伤眼睛的危险