FAUC 213 2-((4-(4-氯苯基)哌嗪-1-基)甲基)吡唑并[1,5-a]吡啶

CAS 337972-47-1 MFCD06798338

化学结构图

337972-47-1
SMILES: ClC1C=CC(=CC=1)N1CCN(CC2C=C3C=CC=CN3N=2)CC1

化学属性

Mol. FormulaC18H19ClN4
Mol. Weight326.82

别名和识别编码

Chemical NameFAUC 213
Synonym 2-[4-(4-Chlorophenyl)piperazin-1-ylmethyl]pyrazolo[1,5-a]pyridine FAUC 213
MDL NumberMFCD06798338
PubChem Substance ID24894864
CAS Number337972-47-1
Chemical Name Translation2-((4-(4-氯苯基)哌嗪-1-基)甲基)吡唑并[1,5-a]吡啶
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分类

  • {SNA} Antagonists, Bioactive Small Molecule Alphabetical Index, Dopaminargics - Antagonists, Dopaminergics, F, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 蛋白质及衍生物
  • {SNA} Antagonists, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Dopaminargics - Antagonists, Dopaminergics, F, GPCR Modulato

相关文献及参考

  • [1]. Frank Boeckler, et al. FAUC 213, a highly selective dopamine D4 receptor full antagonist, exhibits atypical antipsychotic properties in behavioural and neurochemical models of schizophrenia. Psychopharmacology (Berl). 2004 Aug;175(1):7-17.

安全信息

GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P305+P351+P338
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
WGK Germany3
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36 Wear suitable protective clothing 穿戴适当的防护服;
Hazard Codes Xi
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类


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