TETRASODIUM COMBRETASTATIN A1 2',3'-O-DIPHOSPHATE
CAS 288847-34-7 MFCD07368392
化学结构图
SMILES: [Na+].[Na+].[Na+].[Na+].COC1C=CC(/C=C\C2C=C(OC)C(OC)=C(C=2)OC)=C(OP([O-])([O-])=O)C=1OP([O-])([O-])=O
化学属性
| Mol. Formula | C18H18O12P2.4Na |
|---|---|
| Mol. Weight | 580.236 |
| Density | |
| Boiling Point | |
| Melting Point |
别名和识别编码
| Chemical Name | TETRASODIUM COMBRETASTATIN A1 2',3'-O-DIPHOSPHATE |
|---|---|
| Synonym | |
| EC Number | |
| Beilstein Registry Number | |
| Chemical Name Translation |
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相关文献及参考
- [2]. Mao J, et, al. Combretastatin A-1 phosphate, a microtubule inhibitor, acts on both hepatocellular carcinoma cells and tumor-associated macrophages by inhibiting the Wnt/β-catenin pathway. Cancer Lett. 2016 Sep 28;380(1):134-43.
- [3]. Holwell SE, et, al. Anti-tumor and anti-vascular effects of the novel tubulin-binding agent combretastatin A-1 phosphate. Anticancer Res. Nov-Dec 2002;22(6C):3933-40.
- [1]. Stratford MRL, et, al. Quantitative determination of the anticancer prodrug combretastatin A1 phosphate (OXi4503, CA1P), the active CA1 and its glucuronide metabolites in human urine and of CA1 in plasma by HPLC with mass spectrometric d
- [1]. Stratford MRL, et, al. Quantitative determination of the anticancer prodrug combretastatin A1 phosphate (OXi4503, CA1P), the active CA1 and its glucuronide metabolites in human urine and of CA1 in plasma by HPLC with mass spectrometric detection. J Chromatogr B Analyt Technol Biomed Life Sci. 2012 Jun 1;898:1-6.
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