Levocabastine hydrochloride
CAS 79547-78-7 MFCD07787408
化学结构图
SMILES: Cl.C[C@H]1CN(CC[C@@]1(C(O)=O)C1=CC=CC=C1)[C@@H]1CC[C@@](CC1)(C#N)C1=CC=C(F)C=C1
化学属性
| Mol. Formula | C26H29N2O2F·HCl |
|---|---|
| Mol. Weight | 457 |
别名和识别编码
| Chemical Name | Levocabastine hydrochloride |
|---|---|
| CAS Number | 79547-78-7 |
| Synonym | Levocabastine hydrochloride ######## Levophta Levostin R50547 [3S-[1(cis),3α,4β]]-1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenyl-4-piperidinecarboxylic acid Levophta Levostin R50547 [3S-[1(cis),3α,4β]]-1-[4-cyano-4-(4-fluorophenyl)cyclohexyl]-3-methyl-4-phenyl-4-piperidinecarboxylic acid |
| MDL Number | MFCD07787408 |
| Chemical Name Translation |
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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分类
- {SNA} Antagonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, GPCR Modulators, GPCR Proteins, Modulators and Antibodies, Histaminergics, Histaminergics - Antagonists, Johnson & Johnson, L, Membrane Protein Biology Tools, Neuroscience, Neurotransmission, Neurotransmitters, 生化试剂, 生物活性小分子, 细胞信号转导和神经科学, 细胞生物学, 蛋白质及衍生物
- Chiral Reagents
- Heterocycles
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Aromatics
- {SNA} Antagonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience
产品应用
- A histamine H1 receptor antagonist
相关文献及参考
- [2]. Yamauchi R, et al. Effect of beta-lactotensin on acute stress and fear memory. Peptides. 2006;27(12):3176-3182.
- Ash, A., et al.: Br. J. Pharmacol., 27, 427 (1966),
- Davies, M., et al.: Br. J. Clin. Pharmacol., 9, 461 (1980),
- Oda, T., et al.: J. Biol. Chem., 275, 36781 (2000),
- [1]. Folkerts G, et al. Virus-induced airway hyperresponsiveness in the guinea-pig: possible involvement of histamine and inflammatory cells. Br J Pharmacol. 1993;108(4):1083-1093.
- [1]. Folkerts G, et al. Virus-induced airway hyperresponsiveness in the guinea-pig: possible involvement of histamine and inflammatory cells. Br J Pharmacol. 1993;108(4):1083-1093.
- [2]. Yamauchi R, et al. Effect of beta-lactotensin on acute stress and fear memory. Peptides. 2006;27(12):3176-3182.
安全信息
GHS Symbol
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36 Wear suitable protective clothing 穿戴适当的防护服；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
