喹硫平硫氧化物/喹硫平亚砜 喹硫平硫氧化物/喹硫平亚砜
CAS 329216-63-9 MFCD08460237
化学结构图
SMILES: OCCOCCN1CCN(CC1)C1=NC2C=CC=CC=2S(=O)C2C=CC=CC1=2
化学属性
| Mol. Formula | C21H25N3O3S |
|---|---|
| Mol. Weight | 399.51 |
别名和识别编码
| Chemical Name | Quetiapine Sulfoxide |
|---|---|
| CAS Number | 329216-63-9 |
| Synonym | 2-[2-[4-(5-Oxidodibenzo[b,f][1,4]thiazepin-11-yl)-1-piperazinyl]ethoxy]ethanol |
| Chemical Name Translation | 喹硫平硫氧化物/喹硫平亚砜 |
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分类
- Metabolites & Impurities
- Pharmaceuticals
- Intermediates & Fine Chemicals,
产品应用
- A metabolite of Quetiapine, which is used as an antipsychotic.
相关文献及参考
- [2]. Cross AJ, et al. Quetiapine and its metabolite norquetiapine: translation from in vitro pharmacology to in vivo efficacy in rodent models. Br J Pharmacol. 2016 Jan;173(1):155-66.
- Onrust, S., et al.: CNS Drugs, 15, 329
- [1]. Remmerie B, et al. Comparison of Capillary and Venous Drug Concentrations After Administration of a Single Dose of Risperidone, Paliperidone, Quetiapine, Olanzapine, or Aripiprazole. Clin Pharmacol Drug Dev. 2016 Nov;5(6):528-537.
- [1]. Remmerie B, et al. Comparison of Capillary and Venous Drug Concentrations After Administration of a Single Dose of Risperidone, Paliperidone, Quetiapine, Olanzapine, or Aripiprazole. Clin Pharmacol Drug Dev. 2016 Nov;5(6):528-537.
- [2]. Cross AJ, et al. Quetiapine and its metabolite norquetiapine: translation from in vitro pharmacology to in vivo efficacy in rodent models. Br J Pharmacol. 2016 Jan;173(1):155-66.
