Pramipexole (S)-N6-丙基-4,5,6,7-四氢苯并噻唑-2,6-二胺
CAS 104632-26-0 MFCD00869076
化学结构图
SMILES: Cl.CCCN[C@@H]1CC2SC(N)=NC=2CC1
化学属性
| Mol. Formula | C10 |
|---|---|
| Mol. Weight | 211 |
别名和识别编码
| Chemical Name | Pramipexole |
|---|---|
| CAS Number | 104632-26-0 |
| Synonym | (S)-4,5,6,7-Tetrahydro-N6-propyl-2,6-benzothiazolediamine |
| Chemical Name Translation | (S)-N6-丙基-4,5,6,7-四氢苯并噻唑-2,6-二胺 |
| MDL Number | MFCD00869076 |
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分类
- Chiral Reagents
- Inhibitors
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Sulfur & Selenium Compounds
产品应用
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相关文献及参考
- [2]. Takashi Okura, et al. Blood-brain barrier transport of pramipexole, a dopamine D2 agonist. Life Sci. 2007 Apr 3;80(17):1564-71.
- [3]. Ginetta Collo, et al. Ropinirole and Pramipexole Promote Structural Plasticity in Human iPSC-Derived Dopaminergic Neurons via BDNF and mTOR Signaling. Neural Plast. 2018; 2018: 4196961.
- [4]. P M Carvey, et al. Attenuation of levodopa-induced toxicity in mesencephalic cultures by pramipexole. J Neural Transm (Vienna). 1997;104(2-3):209-28.
- [5]. Syed Suhail Andrabi, et al. Pramipexole prevents ischemic cell death via mitochondrial pathways in ischemic stroke. Dis Model Mech. 2019 Aug 1; 12(8): dmm033860.
- Mierau, J., et al.: J. Med. Chem., 30, 494 (1987),
- Schilling, J.C., et al.: Clin. Pharmacol. Ther., 51, 541 (1992),
- [1]. Kvernmo, T., et al
- [1]. Kvernmo, T., et al. A review of the receptor-binding and pharmacokinetic properties of dopamine agonists. Clin Ther, 2006. 28(8): p. 1065-78.
