RepSox ALK 5抑制剂II
CAS 446859-33-2 MFCD09037561
化学结构图
SMILES:
化学属性
| Mol. Formula | C17H13N5 |
|---|---|
| Mol. Weight | 287.32 |
别名和识别编码
| Chemical Name | RepSox |
|---|---|
| Synonym | E-616452; 2-[3-(6-Methyl-2-pyridinyl)-1H-pyrazol-4-yl]-1,5-naphthyridine RepSox |
| MDL Number | MFCD09037561 |
| CAS Number | 446859-33-2 |
| PubChem Substance ID | 329823975 |
| Chemical Name Translation | ALK 5抑制剂II |
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分类
- {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, R, TGF-β Inhibitors, Transforming Growth Factor-β (TGF-β) and Superfamily
- {SA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, R, TGF-β Inhibitors, Transforming Growth Factor-β (TGF-β) and Superfamily
- {SNA} Bioactive Small Molecule Alphabetical Index, Cytokines and Growth Factors, Cytokines, Growth Factors and Hormones, R, TGF-β Inhibitors, Transforming Growth Factor-β (TGF-β) and Superfamily, 生物活性小分子,
相关文献及参考
- Gellibert, F., et al., Design of novel quinazoline derivatives and related analogues as potent and selective ALK5 inhibitors. Bioorg. Med. Chem. Lett. 19 , 2277-81, (2009) 摘要
- Gellibert, F., et al., Identification of 1,5-naphthyridine derivatives as a novel series of potent and selective TGF-beta type I receptor inhibitors. J. Med. Chem. 47 , 4494-506, (2004) 摘要
安全信息
GHS Symbol
- P301+P310+P330
- P301+P310
- H301 Toxic if swallowed 吞食有毒
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
- R25 Toxic if swallowed 吞咽有毒
