Rivaroxaban 利伐沙班
CAS 366789-02-8 MFCD11974010
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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分类
- Chiral Reagents
- Heterocycles
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Sulfur & Selenium Compounds,
产品应用
- Rivaroxaban, also known as BAY 59-7939, is an oral anticoagulant invented and manufactured by Bayer; in a number of countries it is marketed as Xarelto. If approved by the United States FDA, it will be marketed by Ortho-McNeil Pharmaceutical. It is the first available orally active direct factor Xa inhibitor. Rivaroxaban is well absorbed from the gut and maximum inhibition of factor Xa occurs four hours after a dose. The effects lasts 8–12 hours, but factor Xa activity does not return to normal within 24 hours so once-daily dosing is possible.
相关文献及参考
- Ansell, J., et al.: Drugs, 64, 1 (2004),
- Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005),
- Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),