2,8-Dimethyl-5-(2-(6-methylpyridin-3-yl)ethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole dihydrochloride 2,8-二甲基-5-(2-(6-甲基吡啶-3-基)乙基)-2,3,4,5-四氢-1H-吡啶并[4,3-b]吲哚 二盐酸盐
CAS 97657-92-6 MFCD17215933
化学结构图
SMILES:
化学属性
| Mol. Weight | 392.37 (anhydrous basis) |
|---|---|
| Mol. Formula | C21H25N3· 2HCl · xH2O |
别名和识别编码
| Synonym | 2,8-Dimethyl-5-[2-(6-methyl-3-pyridinyl)ethyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole dihydrochloride hydrate Dimebolin dihydrochloride hydrate Dimeboline dihydrochloride hydrate Dimebone dihydrochloride hydrate Dimebon dihydrochloride hydrate |
|---|---|
| Chemical Name | 2,8-Dimethyl-5-(2-(6-methylpyridin-3-yl)ethyl)-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole dihydrochloride |
| MDL Number | MFCD17215933 |
| PubChem Substance ID | 329798824 |
| Chemical Name Translation | 2,8-二甲基-5-(2-(6-甲基吡啶-3-基)乙基)-2,3,4,5-四氢-1H-吡啶并[4,3-b]吲哚 二盐酸盐 |
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分类
- {SNA} Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, DIG-DY, Diversification Ready Pharma-Developed Compounds, Pfizer Compounds, 生物活性小分子, 细胞生物学
- {SNA} Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, DIG-DY, Pfizer Compounds
相关文献及参考
- [1]. Steele JW, et al. Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model. Mol Psychiatry. 2013 Aug;18(8):889-97.
安全信息
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36/39 Wear suitable protective clothing and eye/face protection 穿戴适当的防护服和眼睛/面保护；
GHS Symbol
- P305+P351+P338
- H315 Causes skin irritation 会刺激皮肤
- H302 Harmful if swallowed 吞食有害
- H319 Causes serious eye irritation 严重刺激眼睛
- R36/38 Irritating to eyes and skin 对眼睛和皮肤有刺激性
- R22 Harmful if swallowed 吞咽有害
