Montelukast sodium hydrate
CAS N/A MFCD20527317
化学结构图
SMILES:
化学属性
| Mol. Weight | 608.17 (anhydrous basis) |
|---|---|
| Mol. Formula | C35H35ClNO3S·Na · xH2O |
别名和识别编码
| Synonym | Montelukast sodium hydrate 1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid sodium salt hydrate |
|---|---|
| MDL Number | MFCD20527317 |
| Chemical Name | Montelukast sodium hydrate |
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分类
- Approved Therapeutics/Drug Candidates, Arachidonic Acid Cascade, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Leukotrienes, Lipids in Cell Signaling, M, Merck
- {SNA} Approved Therapeutics/Drug Candidates, Arachidonic Acid Cascade, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Leukotrienes, Lipids in Cell Signaling, M, Merck
- {SNA} Approved Therapeutics/Drug Candidates, Arachidonic Acid Cascade, Bioactive Small Molecule Alphabetical Index, Diversification Ready Pharma-Developed Compounds, Leukotrienes, Lipids in Cell Signaling,
相关文献及参考
- Zhao R, Shi WZ, Zhang YM, Fang SH, Wei EQ., Montelukast, a cysteinyl leukotriene receptor-1 antagonist, attenuates chronic brain injury after focal cerebral ischaemia in mice and rats. J. Pharm. Pharmacol. 4 , 550-7, (2011) 摘要
- Filppula AM, Laitila J, Neuvonen PJ, Backman JT., Reevaluation of the microsomal metabolism of montelukast: major contribution by CYP2C8 at clinically relevant concentrations. Drug Metab. Dispos. 5 , 904-11, (2011)
- Shimbori C, Shiota N, Okunishi H., Effects of montelukast, a cysteinyl-leukotriene type 1 receptor antagonist, on the pathogenesis of bleomycin-induced pulmonary fibrosis in mice. Eur. J. Pharmacol. 1 , 424-30, (2011) 摘要
