2-(4-((7-CHLORO-2-QUINOXALINYL)OXY)-PHENOXY)-PROPIONIC ACID
CAS N/A MFCD05861262
化学结构图
SMILES: CC(OC1C=CC(=CC=1)OC1C=NC2C=CC(Cl)=CC=2N=1)C(O)=O
化学属性
| Mol. Formula | C17H12N2O4ClNa |
|---|---|
| Mol. Weight | 366.73 |
别名和识别编码
| Chemical Name | XK469 |
|---|---|
| Synonym | 2-(4-((7-Chloro-2-quinoxalinyl)oxy)phenoxy)propionic acid 2-(4-((7-Chloro-2-quinoxalinyl)oxy)phenoxy)propionic acid NSC 697887 NSC 697887 |
| MDL Number | MFCD05861262 |
| PubChem Substance ID | 24278776 |
分类
- {SNA} Antitumor Agents, Apoptosis and Cell Cycle, Bioactive Small Molecules, Biochemicals and Reagents, Cancer Research, Cell Biology, Cell Cycle Proteins and Antibodies, Cell Cycle Regulators, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, R to Z, Topoisomerase II-B, X
- {SNA} Apoptosis and Cell Cycle, Bioactive Small Molecule Alphabetical Index, Cell Cycle Proteins, Antibodies and Reagents, Cell Cycle Regulators, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, R to Z, Topoisomerase II-B, X,
相关文献及参考
- Gao, H., et al., XK469, a selective topoisomerase IIβ poison. Proc. Natl. Acad. Sci. U. S. A. 96 , 12168-12173, (1999) 摘要
- Mensah-Osman, E.J., et al., 2-[4-(7-chloro-2-quinoxalinyloxy)phenoxy]-propionic acid (XK469), an inhibitor of topoisomerase (Topo IIβ), regulates Topo IIα and enhances Topo IIα-mediated cytotoxicity. Mol. Cancer Ther. 1 , 1321-1326, (2002)
