Methyl bromoacetate 溴乙酸甲酯
CAS 96-32-2 MFCD00000189
信息真实价格透明
资金保障
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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现货库存
一流品牌服务
分类
- {uni_hamburg} no charge; ester; 1fragment
- 500 Series Drinking Water Methods, Analytical Standards, Analytical/Chromatography, Bromo, Chemical Class, EPA, Halogenated, Method 552, Method Specific
- {SNA} Building Blocks, C2 to C5, Carbonyl Compounds, Chemical Synthesis, Esters, Organic Building Blocks
产品应用
- Methyl bromoacetate was used in the synthesis of novel coumarins. It was also employed in the synthesis of cis-cyclopropanes
相关文献及参考
- Beilstein:2,213
- Short: II/27B
- Addition of the organozinc derivative to nitriles (Blaise reaction), gives ß-amino acrylates, which can be hydrolyzed to ß-keto esters. For conditions allowing the use of hindered nitriles, see: J. Org. Chem., 48, 3833 (1983):
- The reaction with aldehydes in the presence of zinc and tri-n-butylphosphine gives ɑß-unsaturated esters directly: Tetrahedron Lett., 29, 6119 (1988).
- For further reactions of ɑ-bromo esters, see Ethyl bromoacetate, A10448.
安全信息
GHS Symbol
- H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
- H301 Toxic if swallowed 吞食有毒
- H335 May cause respiratory irritation 可能导致呼吸道刺激
- H315 Causes skin irritation 会刺激皮肤
- H300 Fatal if swallowed 吞食致命
- P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
- P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P301+P310
- P301+P330+P331+P310
- P303+P361+P353+P310+P363
- P304+P340+P310
- P305+P351+P338
- P305+P351+P338+P310
- P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
- P403+P233
- P405 Store locked up. 上锁保管。
- P501 Dispose of contents/container to..… 处理内容物/容器.....
- S20 When using do not eat or drink 使用时,不得进食,饮水;
- S23 Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer) 不要吸入气体/烟雾/蒸汽/喷雾;
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
- S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
- R23/24/25 Toxic by inhalation, in contact with skin and if swallowed 吸入,皮肤接触及吞食都有毒
- R25 Toxic if swallowed 吞咽有毒
- R34 Causes burns 会导致灼伤
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R37 Irritating to respiratory system 刺激呼吸道
- R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 15800 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 6,138,1954
其他信息
- Sigma Aldrich:96-32-2(sigmaaldrich)
- Alfa Aesar:溴乙酸甲酯,98+% Methyl bromoacetate, 98+%(96-32-2)
- MOL 文件:96-32-2.mol
- 灭火剂:泡沫、雾状水、砂土、干粉
- 上游原料:四氯化碳 --> 溴乙酸
- 急性毒性:静脉- 小鼠 LDL0: 15.8 毫克/ 公斤
- 检测方法:GC,NMR
- TCI Shanghai:溴乙酸甲酯 Methyl Bromoacetate,>;95.0%(GC)(96-32-2)
- 类别:有毒物品
- 外观性质:无色至黄色液体,有吸湿性。
- MSDS 信息:溴乙酸甲酯(96-32-2).msds
- 溶于甲醇、乙醚、丙酮和苯,实际上不溶于水。
- Acros Organics:溴乙酸甲酯 Methyl bromoacetate, 99%(96-32-2)
- 储运特性:库房通风低温干燥; 与氧化剂、酸类、食品添加剂分开存放
- 用途三:用作有机合成中间体,杀虫剂、除霉剂的溶剂。
- 海关编码:29159080
- 用途二:用于有机合成
- 溴乙酸甲酯价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 xw010389 溴乙酸甲酯;溴醋酸甲酯 50ml 219元 2011/04/16 B0533 溴乙酸甲酯 Methyl Bromoacetate 25G 218元 2011/04/16 B0533 溴乙酸甲酯 Methyl Bromoacetate 500G 1340元
- 下游产品:吲哚-2-羧酸甲酯 --> 4-氯苯氧基乙酰氯 --> 3-吗啉酮 --> 6-三氟甲基吲哚-2-羧酸甲酯 --> 二甲基氨基氯化氢
- 用途一:用作有机合成中间体和溶剂
- F:19
- 毒性分级:高毒
- 凝固点:<-50℃
- 方法一:由乙酸溴化后再与甲醇进行酯化反应而得。将冰醋酸、乙酐、赤磷和几片沸石加入干燥反应器,加热回流,当温度升至60-70℃时开始缓缓滴加溴素,加完后保温约1h。冷却过滤,然后减压蒸馏得溴乙酸。将溴乙酸和甲醇加入四氯化碳中,再加入硫酸,加热回流脱水,脱水完毕,将四氯化碳蒸出,再加入甲醇回流1h,回收甲醇,剩余物经洗涤、干燥后进行减压蒸馏,即得成品。
- 图谱信息:溴乙酸甲酯(96-32-2)Raman光谱 溴乙酸甲酯(96-32-2)质谱(MS) 溴乙酸甲酯(96-32-2)核磁图( 13 CNMR) 溴乙酸甲酯(96-32-2)红外图谱(IR1)
- 可燃性危险特性:明火可燃; 高热放出有毒溴化物气体