CAS 130-15-4 MFCD00001676-1,4-Naphthoquinone 1,4-二萘醌(1,4-萘二醌) TAO{mole}

1,4-Naphthoquinone 1,4-二萘醌(1,4-萘二醌)

CAS 130-15-4 MFCD00001676

化学结构图

SMILES: O=C1C=CC(=O)c2ccccc21

化学属性

Mol. Formula	C10H6O2
Mol. Weight	158.16
Melting Point	119-122°C
Density	1.42
Flash Point	142°(288°F)
TSCA	Yes
Solubility	不溶
Appearance	黄色晶体。微溶于水。溶于乙醚、氯仿、苯、冰醋酸。
Boiling Point	243.22 °C at 760 mmHg

别名和识别编码

Chemical Name	1,4-Naphthoquinone
Synonym	1,4-Naphthoquinone {LY} 1,4-Naphthoquinone {} {LY} 1,4-Naphthoquinone {} {} {LY} 1,4-Naphthoquinone {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {} {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {} {} {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {} {} {} {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {} {} {} {} {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1,4-Naphthoquinone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 1,4-Naphthoquinone
MDL Number	MFCD00001676
Beilstein Registry Number	7,724
CAS Number	130-15-4
EC Number	204-977-6
PubChem Substance ID	8530
Reaxys-RN	878524
Merck Number	14,6395
Chemical Name Translation	1,4-二萘醌(1,4-萘二醌)
Wiswesser Line Notation	L66 BV EVJ
LabNetwork Molecule ID	LN00196373
InChI	InChI=1S/C10H6O2/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6H
Canonical SMILES	O=C1C=CC(C2=C1C=CC=C2)=O

信息真实价格透明资金保障专业采购外包团队在线服务

品牌质保精细包装现货库存一流品牌服务

产品应用

用于有机合成，可制染料中间体蒽醌，农药杀菌剂、除草剂，用于合成橡胶，合成树脂的聚合调节剂等。

安全信息

RTECSQL7175000

WGK Germany3

Hazard Codes 6.1 T+,N T+,N,T

GHS Symbol

Hazard statements

H301+H311
H315 Causes skin irritation 会刺激皮肤
H330 Fatal if inhaled 吸入致命
H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难
H301 Toxic if swallowed 吞食有毒
H335 May cause respiratory irritation 可能导致呼吸道刺激
H400 Verytoxictoaquaticlife 对水生生物毒性非常大。
H319 Causes serious eye irritation 严重刺激眼睛

Personal Protective Equipment Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges

Precautionary statements

P260 Do not breathe dust/fume/gas/mist/vapours/spray. 不要吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西，喝水或吸烟。
P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
P273 Avoid release to the environment. 避免释放到环境中。
P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
P284 Wear respiratory protection.? 佩戴呼吸保护装置。
P301+P310
P302+P350
P304+P340+P310
P305+P351+P338
P308+P313
P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
P337+P313
P403+P233
P501 Dispose of contents/container to..… 处理内容物/容器.....

Signal word Danger

UN Number 2811 UN 2811 6.1/PG 1

Safety Statements

S24 Avoid contact with skin 避免皮肤接触；
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后，立即用大量…（由生产厂家指定）冲洗；
S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；

Risk Statements

R24/25 Toxic in contact with skin and if swallowed 皮肤接触及吞食都有毒
R25 Toxic if swallowed 吞咽有毒
R26 Very toxic by inhalation 吸入极毒
R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
R50 Very toxic to aquatic organisms 对水生生物极毒

Packing GroupI

Hazard Class6.1

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 800 mg/kg/29W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Skin and Appendages - tumors
REFERENCE :
   PIATA8 Proceedings of the Imperial Academy of Tokyo.  (Tokyo, Japan) V.1-21,
   1912-45.  For publisher information, see PJACAW. Volume(issue)/page/year:
   16,309,1940

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
   Exposure," Izmerov, N.F., et al

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 10 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 71,210,1941

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 202 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GTPZAB Gigiena Truda i Professional'nye Zabolevaniya.  Labor Hygiene and
   Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR)
   V.1-36, 1957-1992. For publisher information, see MTPEEI
   Volume(issue)/page/year: 16(5),52,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 5500 ug/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 26,570,1983

TYPE OF TEST

{ha

TYPE OF TEST            : Micronucleus test
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 100 ug/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 393,23,1997

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 5 mg/kg
SEX/DURATION            : female 1 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - ovaries, fallopian tubes
REFERENCE :
   ENDOAO Endocrinology (Baltimore).  (Williams & Wilkins Co., 428 E. Preston
   St., Baltimore, MD 21203) V.1-    1917-  Volume(issue)/page/year:
   57,466,1955

Storage condition 2-8°C {LY} 2-8°C {} {LY} 2-8°C {} {} {LY} 2-8°C {} {} {} {LY} 2-8°C {} {} {} {} {LY} 2-8°C {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} 2-8°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {

其他信息

Hazard Note:Very Toxic
Alfa Aesar:1,4-萘醌,97+%(drywt.),cont.upto5%water 1,4-Naphthoquinone, 97+% (dry wt.), cont. up to 5% water(130-15-4)
用途三:用于有机合成，可制染料中间体蒽醌，农药杀菌剂、除草剂，用于合成橡胶，合成树脂的聚合调节剂等。
1,4-萘醌价格(试剂级):更新日期产品编号产品名称包装价格 2011/08/23 30127080 1，4-萘醌;α-萘醌; 对萘醌; 1,4-萘二酮 25g 470元 2011/08/23 30127081 1，4-萘醌;α-萘醌; 对萘醌; 1,4-萘二酮 25g 506元 2011/04/16 N0040 1,4-萘醌 1,4-Naphthoquinone 25G 211元
存储注意事项:光敏感
F:8
MOL 文件:130-15-4.mol
下游产品:硅酸钠 --> 尼罗红 --> 2,3-二氯-1,4-萘醌 --> 阿托伐醌 --> 3,3'-二氯联苯胺盐酸盐 --> 2-羟基-1,4-萘醌 --> 2,3-二甲基蒽醌
海关编码:29146910
方法一:用1-萘酚、1-萘胺、1,4-氨基萘酚、萘等作原料，经过氧化均可得到萘醌。氧化剂可采用铬酐、重铬酸钠、重铬酸钾、空气等。工业上较为有利的方法是用萘在五氧化二钡存在下催化氧化生产萘醌。
上游原料:三氧化铬 --> 重铬酸钠 --> 重铬酸钾 --> a-萘酚
MSDS 信息:1,4-Naphthalenedione(130-15-4).msds
Sigma Aldrich:130-15-4(sigmaaldrich)
TCI Shanghai:1,4-萘醌 1,4-Naphthoquinone,>;95.0%(T)(130-15-4)
用途二:用于蒽醌生产。萘醌加氯反应生成的2,3-二氯萘醌，是一种重要的农用杀菌剂，用于防治小麦腥黑穗病、稻瘟病、马铃薯晚疫病和蔬菜幼苗的立枯病等。
易溶于热醇、醚、苯、氯仿和二硫化碳；溶于碱溶液呈红棕色；难溶于冷水；微溶于石油醚。能随水蒸气挥发，有苯醌气味。加热至100℃即可升华。
Acros Organics:1,4-萘醌 1,4-Naphthoquinone, contains up to 6% water, 99%(130-15-4)
用途一:用于合成农药杀菌剂2,3-二氯-1,4-萘醌，也用于合成染料中间体蒽醌